DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Myt1 and ern1

DIOPT Version :9

Sequence 1:	NP_647987.2	Gene:	Myt1 / 38649	FlyBaseID:	FBgn0040298	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_001018366.1	Gene:	ern1 / 553551	ZFINID:	ZDB-GENE-050522-431	Length:	292	Species:	Danio rerio

Alignment Length:	155	Identity:	30/155 - (19%)
Similarity:	51/155 - (32%)	Gaps:	54/155 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   374 SRRAVW-----------GRM--CNWKTAAFRYLLYFLEVL------------------------- 400
            ||..||           |.|  |:..|.:....|.|:..|
Zfish     7 SRALVWIITALIWWSHSGLMGFCSSSTVSVPESLLFVSTLDGNLHAVSKISGTIKWTLKEDPVLQ 71

  Fly   401 ---HLCKPITASQPNINIVPS--SPSSKGVPLVPQVEFQLVGSTPIANRD-----------CYAS 449
               |:.:|.....||...:.|  ..:::|:..:|....:||.::|..:.|           .|..
Zfish    72 VPTHVSEPAFLPDPNDGSLYSLGGKNNEGLTKLPFTIPELVQASPCRSSDGILYMGKKQDVRYVV 136

  Fly   450 DFLSGEDPLDLSNQGSPNVINSTPL 474
            |.|:||....|::..:..:..|:.|
Zfish   137 DLLTGEKKQTLTSSYAEMLCPSSSL 161

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Myt1	NP_647987.2	PKc_Myt1	100..349	CDD:270952
Myt1	NP_647987.2	Pkinase	102..349	CDD:278497
ern1	NP_001018366.1	PQQ_2	16..228	CDD:290097	26/146 (18%)
ern1	NP_001018366.1	Luminal_IRE1	38..265	CDD:188875	22/124 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910