DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Myt1 and pak5

DIOPT Version :9

Sequence 1:	NP_647987.2	Gene:	Myt1 / 38649	FlyBaseID:	FBgn0040298	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_998127.1	Gene:	pak5 / 405898	ZFINID:	ZDB-GENE-040426-2085	Length:	711	Species:	Danio rerio

Alignment Length:	317	Identity:	89/317 - (28%)
Similarity:	143/317 - (45%)	Gaps:	50/317 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 SDSSTLPSSPV-------------QAELSTLSLSHFE---------------QCFERLAKLGEGS 112
            |.:.:.||||.             .||.....:||.:               |..:...|:||||
Zfish   387 SHTHSQPSSPYVPPGAYPPPSWGSPAEQPPPRVSHEQFRAALQLVVEPGDPRQGLDSFLKIGEGS 451

  Fly   113 FGEVFQVRDRSDGQLYAVKISKQLFRGEQYRAERLEEV---RRYEEFSGHENCIRFIRAWEQYDR 174
            .|.|....::..|:..|||  |...|.:|.|.....||   |.|.    |||.:....::...|.
Zfish   452 TGIVCIATEKHSGKQVAVK--KMDLRKQQRRELLFNEVVIMRDYH----HENVVDMYNSYLVGDE 510

  Fly   175 LYMQMELCRESLEQYLLRCQRIPEERIWHILLDLLRGLKSLHDRNLIHLDIKLDNVLIGEDDETC 239
            |::.||.........::...|:.||:|..:.|.:|:.|..||.:.:||.|||.|::|:..|.. .
Zfish   511 LWVVMEFLEGGALTDIVTHTRMNEEQIATVCLSVLKALSYLHTQGVIHRDIKSDSILLTSDGR-I 574

  Fly   240 KLADFGLVIDVDR-ANSHHATEGDSRYMAPEILQG-HFSKAADIFSLGIAMLELA----CYMDLP 298
            ||:|||....|.: .....:..|...:||||::.. .:....||:||||.::|:.    .|.:.|
Zfish   575 KLSDFGFCAQVSKEVPKRKSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMVDGEPPYFNEP 639

  Fly   299 SNGPL--WHELRHGILPE-EFINKISLELQSVIKSMMKPDPAQRPTAEQLLSHPKLQ 352
               ||  ...:|..:.|. :..:|:|..|::.:..|:..:|:||.:|.:||.:|.|:
Zfish   640 ---PLQAMRRIRDNLPPRLKESHKVSSVLRAFLDLMLVREPSQRASALELLQNPFLK 693

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Myt1	NP_647987.2	PKc_Myt1	100..349	CDD:270952	78/260 (30%)
Myt1	NP_647987.2	Pkinase	102..349	CDD:278497	77/258 (30%)
pak5	NP_998127.1	CRIB_PAK_like	9..55	CDD:238526
		STKc_PAK5	418..709	CDD:132989	82/286 (29%)
		S_TKc	446..692	CDD:214567	78/255 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910