Protein Alignment Myt1 and Wee2

DIOPT Version :9

• Sequence 1: NP_647987.2
• Gene: Myt1 / 38649
• FlyBaseID: FBgn0040298
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_958758.2
• Gene: Wee2 / 381759
• MGIID: 3027899
• Length: 555
• Species: Mus musculus
• Alignment Length: 431
• Identity: 112/431 - (25%)
• Similarity: 182/431 - (42%)
• Gaps: 103/431 - (23%)

  Fly     3 KHHRLPLPELHDDKHRHKQCNGENSNRFRPPKY-----------KTRGYVAVDNNNLNRSQSLGS 56
            :|.||....|.|:|   ...:..|.|.|.|..|           |||.|:
Mouse   128 RHMRLTPASLMDEK---TSLSLVNINPFTPETYRKLLLQSKGKRKTRDYL--------------- 174

  Fly    57 CSTNSSQIAHAISFRDAGCSDSSTLPSSPVQAEL--STLSLSHFEQCFERLAKLGEGSFGEVFQV 119
                          .:.|..:|.::...|.:..:  .|...|.:|:.|..:.|:|.|.||.|::.
Mouse   175 --------------EETGEEESKSVQWLPAKRSILQETNMASRYEKEFFEIEKIGVGEFGTVYKC 225

  Fly   120 RDRSDGQLYAVKISKQLFRGEQYRAERLEEVRRYEEFSGHENCIRFIRAWEQYDRLYMQMELC-- 182
            ..|.||.:||:|.|.:.|.|.....: |.||..:.....|.:.:|:..:|.:.|.:.:|.|.|
Mouse   226 IKRLDGCIYAIKRSAKSFSGLSNELD-LHEVYAHAVLGHHPHVVRYYSSWIEDDHVVIQNEYCNG 289

  Fly   183 ---RESLEQYLLRCQRIPEERIWHILLDLLRGLKSLHDRNLIHLDIKLDNVLI-----------G 233
               :.::.:.........|.::..|||.:..|||.:|:..::|||||..|:.|           .
Mouse   290 GSLQAAISENTASNNHFQEPKLKDILLQISLGLKYIHNSGMVHLDIKPSNIFICHKMQCDSPVGP 354

  Fly   234 EDDET-----------CKLADFGLVIDVDRANSHHAT--------EGDSRYMAPEILQGHFS--K 277
            |:.|:           .|:.|.|           |||        |||:|::|.||||.::.  .
Mouse   355 EEAESEADWFLNASVMYKIGDLG-----------HATSISKPKVEEGDTRFLANEILQENYQHLP 408

  Fly   278 AADIFSLGIAMLELACYMDLPSNGPLWHELRHGILPEEFINKISLELQSVIKSMMKPDPAQRPTA 342
            .||||:||:.:...|....||.||.:||.:|.|..| |...::|.:...::|:|:.|.|.:||:|
Mouse   409 KADIFALGLTIAVAAGAESLPINGDMWHHIRKGNFP-EISQELSDDFYGLLKNMIHPAPKERPSA 472

  Fly   343 EQL----LSHPKLQYLQKKRKSL----MNFSMLSRSFRRSR 375
            ..|    :..|.|:...:.:|.|    ...:.|.|..:::|
Mouse   473 AALARSRILWPFLEKTDELQKQLNLEKSKTATLKRELKKAR 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myt1	NP_647987.2	PKc_Myt1	100..349	CDD:270952	84/289 (29%)
		Pkinase	102..349	CDD:278497	84/287 (29%)
Wee2	NP_958758.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..112
		Nuclear localization signal	167..169		0/1 (0%)
		PKc_like	207..477	CDD:389743	84/282 (30%)
		Nuclear export signal	310..324		5/13 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0601
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810