DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Myt1 and Map4k1

DIOPT Version :9

Sequence 1:	NP_647987.2	Gene:	Myt1 / 38649	FlyBaseID:	FBgn0040298	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_001099713.1	Gene:	Map4k1 / 292763	RGDID:	1305463	Length:	827	Species:	Rattus norvegicus

Alignment Length:	270	Identity:	78/270 - (28%)
Similarity:	130/270 - (48%)	Gaps:	38/270 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 FERLAKLGEGSFGEVFQVRDRSDGQLYAVKISKQLFRGEQYRAERLEEVRRYE------EFSGHE 160
            ::.|.:||.|::||||:.||         |:||.|...:..:.|..::|...:      :...|.
  Rat    17 YDLLQRLGGGTYGEVFKARD---------KVSKDLVALKMVKMEPDDDVSTLQKEILMLKSCRHA 72

  Fly   161 NCIRFIRAWEQYDRLYMQMELC-RESLEQYLLRCQRIPEERIWHILLDLLRGLKSLHDRNLIHLD 224
            |.:.:..::....:|::.||.| ..||:........:.|.:|.::..::|:||..||.:..||.|
  Rat    73 NIVAYHGSYLWLQKLWICMEFCGAGSLQDIYQVTGSLSELQISYVCREVLQGLAYLHSQKKIHRD 137

  Fly   225 IKLDNVLIGEDDETCKLADFGLVIDVDRANSHHAT-EGDSRYMAPEI----LQGHFSKAADIFSL 284
            ||..|:||.:..|. ||||||:...:....:...: .|...:||||:    |:|.:::..||:||
  Rat   138 IKGANILINDSGEV-KLADFGISAQIGATLARRLSFIGTPYWMAPEVAAVALKGGYNELCDIWSL 201

  Fly   285 GIAMLELACYMDLPSNGPLW--HELR-------HGILPEEF--INKISLELQSVIKSMMKPDPAQ 338
            ||..:|||     ....||:  |.||       .|..|...  ..|.|....:.:|..:..:..:
  Rat   202 GITAIELA-----ELQPPLFDVHPLRVLFLMTKSGYQPPRLKEKGKWSSSFHNFVKVTLTKNSKK 261

  Fly   339 RPTAEQLLSH 348
            ||:|.::|||
  Rat   262 RPSATKMLSH 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Myt1	NP_647987.2	PKc_Myt1	100..349	CDD:270952	78/270 (29%)
Myt1	NP_647987.2	Pkinase	102..349	CDD:278497	78/270 (29%)
Map4k1	NP_001099713.1	STKc_MAP4K3_like	16..274	CDD:270788	78/270 (29%)
		S_TKc	17..274	CDD:214567	78/270 (29%)
		CNH	506..813	CDD:214481
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910