Protein Alignment Myt1 and STK36

DIOPT Version :9

• Sequence 1: NP_647987.2
• Gene: Myt1 / 38649
• FlyBaseID: FBgn0040298
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_001356352.1
• Gene: STK36 / 27148
• HGNCID: 17209
• Length: 1315
• Species: Homo sapiens
• Alignment Length: 467
• Identity: 108/467 - (23%)
• Similarity: 186/467 - (39%)
• Gaps: 110/467 - (23%)

  Fly   105 LAKLGEGSFGEVFQVRDRSDGQLYAVKISKQLFRGEQYRAERLEEVRRYEEFS---GHENCIRFI 166
            |..:||||||.|::.|.:...|:.|:|...:|.|.|    :.|..::|..|..   .|.|.:..:
Human     7 LEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSE----KELRNLQREIEIMRGLRHPNIVHML 67

  Fly   167 RAWEQYDRLYMQMELCRESLEQYLLRCQRIPEERIWHILLDLLRGLKSLHDRNLIHLDIKLDNVL 231
            .::|....:.:..:.....|.|.|....::||:::..|...|:..|..||...::|.|:|..|:|
Human    68 DSFETDKEVVVVTDYAEGELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHRILHRDMKPQNIL 132

  Fly   232 IGEDDETCKLADFGLVIDVDRANSHH-----ATEGDSRYMAPEILQGH-FSKAADIFSLGIAMLE 290
            :.:.. ..||.|||..    ||.|.:     :.:|...||:||:::.. :...||::|:|..:.|
Human   133 LAKGG-GIKLCDFGFA----RAMSTNTMVLTSIKGTPLYMSPELVEERPYDHTADLWSVGCILYE 192

  Fly   291 LACYMDLPSNGPLW----HELRHGIL--PEEFINKISLELQSVIKSMMKPDPAQRPTAEQLLSH- 348
            ||.     ...|.:    .:|...||  |..:.:.||...::.::.::..||.||.:...||.|
Human   193 LAV-----GTPPFYATSIFQLVSLILKDPVRWPSTISPCFKNFLQGLLTKDPRQRLSWPDLLYHP 252

  Fly   349 --------------------------PKLQYLQKKRKSLM----NFS-MLSRSFRR-SRRAVWGR 381
                                      |:||.|:.::...:    |.| :|:::::| :..|:..:
Human   253 FIAGHVTIITEPAGPDLGTPFTSRLPPELQVLKDEQAHRLAPKGNQSRILTQAYKRMAEEAMQKK 317

  Fly   382 MCNWKTAAFRYLLYFLEVLHLCKPITASQPNINIVP---------------SSPSSKGVPLVPQV 431
            ..|...|     |...:......|.||..|.:...|               ||.:..|...||
Human   318 HQNTGPA-----LEQEDKTSKVAPGTAPLPRLGATPQESSLLAGILASELKSSWAKSGTGEVP-- 375

  Fly   432 EFQLVGSTPIANR---DCYASDFLSGEDPLDLSNQGSPNVINSTPLNTNQGKSRLDLLKNNVDSM 493
                  |.|..||   ||   :....|:..::..|.|.:|:              ||.....||.
Human   376 ------SAPRENRTTPDC---ERAFPEERPEVLGQRSTDVV--------------DLENEEPDSD 417

  Fly   494 GRYVHVHDFESP 505
            ..:.|:.:...|
Human   418 NEWQHLLETTEP 429

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myt1	NP_647987.2	PKc_Myt1	100..349	CDD:270952	70/285 (25%)
		Pkinase	102..349	CDD:278497	70/285 (25%)
STK36	NP_001356352.1	STKc_STK36	2..254	CDD:270904	70/260 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	312..347		8/39 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	365..387		8/29 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910