DRSC/TRiP Functional Genomics Resources

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Protein Alignment Myt1 and Camk1d

DIOPT Version :9

Sequence 1:NP_647987.2 Gene:Myt1 / 38649 FlyBaseID:FBgn0040298 Length:533 Species:Drosophila melanogaster
Sequence 2:NP_796317.2 Gene:Camk1d / 227541 MGIID:2442190 Length:385 Species:Mus musculus


Alignment Length:395 Identity:104/395 - (26%)
Similarity:176/395 - (44%) Gaps:74/395 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    71 RDAGCSDSSTLPSSPVQAELSTLSLSHFEQCFERLAKLGEGSFGEVFQVRDRSDGQLYAVK-ISK 134
            |:.|.|.||.    ..|||       ..::.||....||.|:|.||....:::.|:|:||| |.|
Mouse     3 RENGESSSSW----KKQAE-------DIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPK 56

  Fly   135 QLFRGEQYRAE-RLEEVRRYEEFSGHENCIRFIRAWEQYDRLYMQMELCRESLEQYLLRCQRIPE 198
            :..:|::...| .:..:|:.:    |||.:.....:|..:.||:.|:|.... |.:    .||.|
Mouse    57 KALKGKESSIENEIAVLRKIK----HENIVALEDIYESPNHLYLVMQLVSGG-ELF----DRIVE 112

  Fly   199 ERIW------HILLDLLRGLKSLHDRNLIHLDIKLDNVLIGEDDETCK--LADFGLVIDVDRANS 255
            :..:      .::..:|..:..||...::|.|:|.:|:|....||..|  ::||||.....:.:.
Mouse   113 KGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDV 177

  Fly   256 HHATEGDSRYMAPEIL-QGHFSKAADIFSLGIAMLELACYMDLPSNGPLWHE----LRHGILPEE 315
            .....|...|:|||:| |..:|||.|.:|:|:....|.|     ...|.:.|    |...||..|
Mouse   178 MSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLC-----GYPPFYDENDSKLFEQILKAE 237

  Fly   316 ------FINKISLELQSVIKSMMKPDPAQRPTAEQLLSHPKL---QYLQKKRKSLMNFSMLSRSF 371
                  :.:.||...:..|:::|:.||.:|.|.||...||.:   ..|.|.....:: :.:.::|
Mouse   238 YEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTALSKNIHESVS-AQIRKNF 301

  Fly   372 RRSRRAVWGRMCNWKTAAFRYLLYFLEVLHLCKPITASQPNIN-----------IVPSS-----P 420
            .:|:   |.:..| .||..|:    :..|.|...:.:|..:::           :.||:     .
Mouse   302 AKSK---WRQAFN-ATAVVRH----MRRLQLGSSLDSSNASVSSNLSLASQKDCLAPSTLCSFLS 358

  Fly   421 SSKGV 425
            ||.||
Mouse   359 SSSGV 363

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Myt1NP_647987.2 PKc_Myt1 100..349 CDD:270952 76/269 (28%)
Pkinase 102..349 CDD:278497 76/267 (28%)
Camk1dNP_796317.2 STKc_CaMKI_delta 12..312 CDD:271070 87/329 (26%)
Autoinhibitory domain. /evidence=ECO:0000250 279..319 9/48 (19%)
Calmodulin-binding. /evidence=ECO:0000250 299..320 7/28 (25%)
Nuclear export signal. /evidence=ECO:0000250 318..324 1/9 (11%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 363..385 1/1 (100%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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