DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Myt1 and Map4k3

DIOPT Version :9

Sequence 1:	NP_647987.2	Gene:	Myt1 / 38649	FlyBaseID:	FBgn0040298	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	XP_036016462.1	Gene:	Map4k3 / 225028	MGIID:	2154405	Length:	935	Species:	Mus musculus

Alignment Length:	269	Identity:	75/269 - (27%)
Similarity:	140/269 - (52%)	Gaps:	16/269 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 LSLSHFEQCFERLAKLGEGSFGEVFQVRDRSDGQLYAVKISKQLFRGEQYRAERLEEVRRYEEFS 157
            ||..:.::.||.:.::|.|::|:|::.|:.:.|:|.|:|:.| |..||.:...:.|.:...:  .
Mouse     7 LSRRNPQEDFELIQRIGSGTYGDVYKARNVNTGELAAIKVIK-LEPGEDFAVVQQEIIMMKD--C 68

  Fly   158 GHENCIRFIRAWEQYDRLYMQMELC-RESLEQYLLRCQRIPEERIWHILLDLLRGLKSLHDRNLI 221
            .|.|.:.:..::.:.|:|::.||.| ..||:........:.|.:|.::..:.|:||..||.:..:
Mouse    69 KHPNIVAYFGSYLRRDKLWICMEFCGGGSLQDIYHVTGPLSELQIAYVSRETLQGLYYLHSKGKM 133

  Fly   222 HLDIKLDNVLIGEDDETCKLADFGLVIDVDRANSHHAT-EGDSRYMAPEIL----QGHFSKAADI 281
            |.|||..|:|: .|:...||||||:...:....:...: .|...:||||:.    :|.:::..|:
Mouse   134 HRDIKGANILL-TDNGHVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDL 197

  Fly   282 FSLGIAMLELA----CYMDLPSNGPLWHELRHGILPEEFINKI--SLELQSVIKSMMKPDPAQRP 340
            :::||..:|||    ...||.....|:...:....|.:..:|:  |......:|..:..:|.:||
Mouse   198 WAVGITAIELAELQPPMFDLHPMRALFLMTKSNFQPPKLKDKLKWSNSFHHFVKMALTKNPKKRP 262

  Fly   341 TAEQLLSHP 349
            .||:||.||
Mouse   263 NAEKLLQHP 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Myt1	NP_647987.2	PKc_Myt1	100..349	CDD:270952	71/260 (27%)
Myt1	NP_647987.2	Pkinase	102..349	CDD:278497	71/258 (28%)
Map4k3	XP_036016462.1	STKc_MAP4K3_like	15..273	CDD:270788	73/261 (28%)
Map4k3	XP_036016462.1	CNH	572..915	CDD:214481
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910