DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Myt1 and cst-1

DIOPT Version :9

Sequence 1:	NP_647987.2	Gene:	Myt1 / 38649	FlyBaseID:	FBgn0040298	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_001024575.2	Gene:	cst-1 / 180708	WormBaseID:	WBGene00017472	Length:	497	Species:	Caenorhabditis elegans

Alignment Length:	319	Identity:	94/319 - (29%)
Similarity:	146/319 - (45%)	Gaps:	67/319 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 STNSSQIAHAISFRDAGCSDSSTLPSSPVQAELSTLSLSHFEQCFERLAKLGEGSFGEVFQVRDR 122
            ||:||:........|....|||.|...|             |:.|:.:.||||||:|.|.:...|
Worm     4 STDSSRRNSEEGSSDGFKLDSSALNKPP-------------EEVFDIVGKLGEGSYGSVHKAIHR 55

  Fly   123 SDGQLYAVK---ISKQLFRGEQYRAERLEEVRRYEEFSGHENC-----IRFIRAWEQYDRLYMQM 179
            ..|.:.|:|   :...           |:|:  .:|.|..:.|     :::..::.::..|::.|
Worm    56 ESGHVLAIKKVPVDTD-----------LQEI--IKEISIMQQCKSKYVVKYYGSYFKHSDLWIVM 107

  Fly   180 ELCRESLEQYLLRCQRIP--EERIWHILLDLLRGLKSLHDRNLIHLDIKLDNVLIGEDDETCKLA 242
            |.|.......::|.:|.|  |:.|..:|.|.|:||:.|||...||.|||..|:|:..|. ..|||
Worm   108 EYCGAGSISDIMRARRKPLSEQEISAVLRDTLKGLQYLHDLKKIHRDIKAGNILLNTDG-IAKLA 171

  Fly   243 DFGLVIDV-DRANSHHATEGDSRYMAPEILQ--GHFSKAADIFSLGIAMLELA----CYMDLPSN 300
            |||:...: |.....:...|...:||||:::  |:.:| |||:||||..:|:|    .|.|:
Worm   172 DFGVAGQLTDTMAKRNTVIGTPFWMAPEVIEEIGYDTK-ADIWSLGITAIEMAEGRPPYSDI--- 232

  Fly   301 GPLWHELRHGIL-----------PEEFINKISLELQSVIKSMMKPDPAQRPTAEQLLSH 348
                |.:|...:           |||:    |.|....|:|.:...|.:|.||.:|..|
Worm   233 ----HPMRAIFMIPTKPPPTFKKPEEW----SSEFNDFIRSCLIKKPEERKTALRLCEH 283

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Myt1	NP_647987.2	PKc_Myt1	100..349	CDD:270952	83/277 (30%)
Myt1	NP_647987.2	Pkinase	102..349	CDD:278497	83/275 (30%)
cst-1	NP_001024575.2	STKc_MST1_2	31..286	CDD:132943	85/292 (29%)
		S_TKc	35..286	CDD:214567	83/275 (30%)
		Mst1_SARAH	446..493	CDD:288481
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910