DRSC/TRiP Functional Genomics Resources

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Protein Alignment Myt1 and Mak

DIOPT Version :9

Sequence 1:NP_647987.2 Gene:Myt1 / 38649 FlyBaseID:FBgn0040298 Length:533 Species:Drosophila melanogaster
Sequence 2:XP_006516931.1 Gene:Mak / 17152 MGIID:96913 Length:647 Species:Mus musculus


Alignment Length:446 Identity:108/446 - (24%)
Similarity:176/446 - (39%) Gaps:104/446 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   102 FERLAKLGEGSFGEVFQVRDRSDGQLYAVKISKQLFRGEQYRAERLEEVRRYEEFSGHENCIRFI 166
            :..:.:||:|::|.|...:....|:|.|:|..|:.|.... ....|.||:..::.: |.|.|:..
Mouse     4 YTTMKQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWD-ECMNLREVKSLKKLN-HANVIKLK 66

  Fly   167 RAWEQYDRLYMQMELCRESLEQYLL-RCQRIPEERIWHILLDLLRGLKSLHDRNLIHLDIKLDNV 230
            ....:.|.||...|..:|:|.|.:. |.:..||..|.:|:..:|:||..:|.....|.|:|.:|:
Mouse    67 EVIRENDHLYFVFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENL 131

  Fly   231 L-IGEDDETCKLADFGLVIDVDRANSHHATEGDSR-YMAPEIL--QGHFSKAADIFSLGIAMLEL 291
            | :|  .|..|:|||||..:: |:...:.....:| |.|||:|  ...:|...|::::|..|.||
Mouse   132 LCMG--PELVKIADFGLAREL-RSQPPYTDYVSTRWYRAPEVLLRSSVYSSPIDVWAVGSIMAEL 193

  Fly   292 ACYMDL---------------------PSNGPLWHELRHGI-------LP---EEFINKISLELQ 325
            ..:..|                     .|:.|..::|...:       :|   :..|...|.|..
Mouse   194 YTFRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQCIPINLKTLIPNASSEAI 258

  Fly   326 SVIKSMMKPDPAQRPTAEQLLSHPKLQ----------YLQKKR---KSLMNFSMLSRSFRRSRRA 377
            .::..|:..||.:||||.|.|.||..|          :|..|:   |.|........|..|..:.
Mouse   259 QLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGSSAHHLDTKQTLHKQLQPLEPKPSSSERDPKP 323

  Fly   378 VWGRMCNWKTAAFRYLLYFLEVL------------HLCKPITASQPNINIVP-SSPSSKGVPLVP 429
            :                  ..:|            |  :|:...||..|.|. ..|..:|....|
Mouse   324 L------------------PNILDQPAGQPQPKQGH--QPLQTIQPPQNTVTHPPPKQQGHQKPP 368

  Fly   430 QVEF-QLVGSTPI----------ANRDCYASDFLSG------EDPLDLSNQGSPNV 468
            |..| .::.:.|:          |.|....:.|.||      ||.|..|:...|::
Mouse   369 QTMFPSIIKTIPVNSVSTLGHKGARRRWGQTVFKSGDSCDDIEDDLGASHSKKPSM 424

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Myt1NP_647987.2 PKc_Myt1 100..349 CDD:270952 76/282 (27%)
Pkinase 102..349 CDD:278497 76/282 (27%)
MakXP_006516931.1 STKc_MAK_like 4..284 CDD:270824 78/284 (27%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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