DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Myt1 and AgaP_AGAP010874

DIOPT Version :9

Sequence 1:	NP_647987.2	Gene:	Myt1 / 38649	FlyBaseID:	FBgn0040298	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	XP_309828.4	Gene:	AgaP_AGAP010874 / 1271082	VectorBaseID:	AGAP010874	Length:	636	Species:	Anopheles gambiae

Alignment Length:	393	Identity:	107/393 - (27%)
Similarity:	170/393 - (43%)	Gaps:	72/393 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 HHRLPLPELHDDKHRH--KQCNGENSNRFRPPKYKTRGYVAVDNNN--------LNRSQSLGSCS 58
            ||.      |...|.|  :|...:...:.:|...:..|...:.|::        ::..|.:.|.|
Mosquito   252 HHH------HQHAHHHGAQQQQQQQQQQMQPTPLQMGGNNQMPNHHHHHNHNAMVHNHQKMPSPS 310

  Fly    59 TNSSQIAHAISFRDAGCSDSSTLPSS------PVQAELSTLSLSHF-------------EQCFER 104
            ::||        ..|..|.:||..|.      ||:.| ..|:...|             .:..|.
Mosquito   311 SSSS--------TGAPTSTASTTQSGQSQQQPPVKTE-QRLTHEQFRAALQMVVSAGDPRENLEN 366

  Fly   105 LAKLGEGSFGEVFQVRDRSDGQLYAVKISKQLFRGEQYRAERL-EEV---RRYEEFSGHENCIRF 165
            ..|:||||.|.|....|:|.|:..||   ||:...:|.|.|.| .||   |.|.    |.|.:..
Mosquito   367 YTKIGEGSTGTVCIATDKSTGRQVAV---KQMDLRKQQRRELLFNEVVIMRDYH----HPNIVET 424

  Fly   166 IRAWEQYDRLYMQMELCRESLEQYLLRCQRIPEERIWHILLDLLRGLKSLHDRNLIHLDIKLDNV 230
            ..::...|.|::.||.........::...|:.||:|..:....|:.|..||.:.:||.|||.|::
Mosquito   425 YSSFLVNDELWVVMEFLEGGALTDIVTHSRMDEEQIATVCKQCLKALSYLHSQGVIHRDIKSDSI 489

  Fly   231 LIGEDDETCKLADFGLVIDVDR-ANSHHATEGDSRYMAPEILQG-HFSKAADIFSLGIAMLELAC 293
            |:..|... ||:|||....|.: .....:..|...:|:||::.. .:....||:||||.::|:
Mosquito   490 LLASDGRV-KLSDFGFCAQVSQELPKRKSLVGTPYWMSPEVISRLPYGPEVDIWSLGIMVIEM-- 551

  Fly   294 YMDLPSNGPLWHE-----LR--HGILPEEFIN--KISLELQSVIKSMMKPDPAQRPTAEQLLSHP 349
               :....|.::|     :|  ..:.|.:..|  |:|..||:.:..|:..||.||.||.:||:||
Mosquito   552 ---IDGEPPFFNEPPLQAMRRIRDMPPPKLKNSHKVSSRLQNFLDRMLVRDPVQRATAAELLAHP 613

  Fly   350 KLQ 352
            .|:
Mosquito   614 FLR 616

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Myt1	NP_647987.2	PKc_Myt1	100..349	CDD:270952	80/263 (30%)
Myt1	NP_647987.2	Pkinase	102..349	CDD:278497	80/261 (31%)
AgaP_AGAP010874	XP_309828.4	CRIB_PAK_like	9..54	CDD:238526
		STKc_PAK_II	356..616	CDD:270815	82/272 (30%)
		S_TKc	369..615	CDD:214567	81/258 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910