DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Myt1 and AgaP_AGAP013266

DIOPT Version :9

Sequence 1:	NP_647987.2	Gene:	Myt1 / 38649	FlyBaseID:	FBgn0040298	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	XP_003436241.1	Gene:	AgaP_AGAP013266 / 11175450	VectorBaseID:	AGAP013266	Length:	1140	Species:	Anopheles gambiae

Alignment Length:	208	Identity:	59/208 - (28%)
Similarity:	97/208 - (46%)	Gaps:	29/208 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   175 LYMQMELC-RESLEQYL-LRCQRIPEERIWHILLDLLRGLKSLHDRNLIHLDIKLDNVLIGEDDE 237
            ||:||:|| ::||:::| |.......::|..|...::.|::.:|.:.|||.|:|..|:....|..
Mosquito   869 LYIQMQLCHKQSLKEWLSLNGFPARRDKIVPIFEQIVAGVEYVHLKGLIHRDLKPSNIFFSLDGR 933

  Fly   238 TCKLADFGLVID-----VDRANS--------HHATEGDSRYMAPEILQG-HFSKAADIFSLGIAM 288
             .|:.|||||.|     .|..|:        |....|...||:||.|:| .:....||:|||:.:
Mosquito   934 -IKIGDFGLVTDSSDLQYDSENNMPTMVPNRHTRQVGTQLYMSPEQLKGLPYDYKVDIYSLGLIL 997

  Fly   289 LELACYMDLPSNGPLWHEL------RHGILPEEFINKISLELQSVIKSMMKPDPAQRPTAEQLLS 347
            .||     |.|.|.....:      |....|:.|......|.: ::..|:...|.:|||...:.:
Mosquito   998 FEL-----LVSFGTEMERICTLKNVRKSKFPDNFEEDHECEFK-LLSLMLSEAPNKRPTTFGIKA 1056

  Fly   348 HPKLQYLQKKRKS 360
            ||..:.:...:.:
Mosquito  1057 HPPFKRIPSNKST 1069

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Myt1	NP_647987.2	PKc_Myt1	100..349	CDD:270952	57/195 (29%)
Myt1	NP_647987.2	Pkinase	102..349	CDD:278497	57/195 (29%)
AgaP_AGAP013266	XP_003436241.1	Luminal_EIF2AK3	20..339	CDD:188874
		PKc_like	537..>630	CDD:304357
		S_TKc	<865..1060	CDD:214567	59/197 (30%)
		STKc_EIF2AK	<867..1051	CDD:270898	56/188 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910