DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Myt1 and rps6ka3

DIOPT Version :9

Sequence 1:	NP_647987.2	Gene:	Myt1 / 38649	FlyBaseID:	FBgn0040298	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	XP_031752603.1	Gene:	rps6ka3 / 100496161	XenbaseID:	XB-GENE-480947	Length:	737	Species:	Xenopus tropicalis

Alignment Length:	368	Identity:	101/368 - (27%)
Similarity:	158/368 - (42%)	Gaps:	71/368 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LPLPELHD--DKHRHKQCNGENSNRFRPPKYKTRGYVAVDNNNLNRSQSLGSCSTNSSQIAHAIS 69
            :||.:|.|  .|...::...||..:|....       ..|.:|.|..:.    :.|...|.|.:.
Frog     1 MPLAQLADPWQKVPVQKVGSENGQQFADES-------MCDEDNENNDEG----NINEIAITHHVK 54

  Fly    70 FRDAGCSDSSTLPSSPVQAELSTLSLSHFEQCFERLAKLGEGSFGEVFQVRDRSD---GQLYAVK 131
                    .....:.|.|              ||.|..||:||||:||.||..|.   |||||:|
Frog    55 --------EGHEKADPSQ--------------FELLKVLGQGSFGKVFLVRKISGTDAGQLYAMK 97

  Fly   132 ISKQLFRGEQYRA----ER--LEEVRRYEEFSGHENCIRFIRAWEQYDRLYMQMELCR-ESLEQY 189
            :.|:.....:.|.    ||  |.||       .|...::...|::...:||:.::..| ..|...
Frog    98 VLKKATLKVRDRVRTKMERDILVEV-------NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTR 155

  Fly   190 LLRCQRIPEERIWHILLDLLRGLKSLHDRNLIHLDIKLDNVLIGEDDETCKLADFGLVID-VDRA 253
            |.:.....||.:.:.|.:|...|..||...:|:.|:|.:|:|:.|:.. .||.||||..: :|..
Frog   156 LSKEVMFTEEDVKYYLAELALALDHLHSLGIIYRDLKPENILLDEEGH-IKLTDFGLSKESIDHE 219

  Fly   254 NSHHATEGDSRYMAPEIL--QGHFSKAADIFSLGIAMLELACYMDLPSNGPLWHELRHGILP--- 313
            ...::..|...|||||::  :|| :::||.:|.|:.|.|:.. ..||..|....|....||.
Frog   220 KKAYSFCGTVEYMAPEVVNRRGH-TQSADWWSFGVLMFEMLT-GTLPFQGKDRKETMTMILKAKL 282

  Fly   314 --EEFINKISLELQSVIKSMMKPDPAQRPTA-----EQLLSHP 349
              .:|:..   |.||:::.:.|.:|..|..|     |::..||
Frog   283 GMPQFLTP---EAQSLLRMLFKRNPTNRLGAGPDGVEEIKRHP 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Myt1	NP_647987.2	PKc_Myt1	100..349	CDD:270952	83/271 (31%)
Myt1	NP_647987.2	Pkinase	102..349	CDD:278497	83/269 (31%)
rps6ka3	XP_031752603.1	STKc_RSK_N	69..385	CDD:270734	82/267 (31%)
rps6ka3	XP_031752603.1	STKc_RSK2_C	399..737	CDD:271078
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910