DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Myt1 and prkcq

DIOPT Version :9

Sequence 1:	NP_647987.2	Gene:	Myt1 / 38649	FlyBaseID:	FBgn0040298	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	XP_012813823.2	Gene:	prkcq / 100038268	XenbaseID:	XB-GENE-487643	Length:	699	Species:	Xenopus tropicalis

Alignment Length:	357	Identity:	82/357 - (22%)
Similarity:	145/357 - (40%)	Gaps:	69/357 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 STNSSQIAHAISFRDAGCSDSSTLPS-----SPVQAEL----STLSLSHFEQCFERLAKLGEGSF 113
            :|....|..:|.....|.|..|.:.|     ||.:.||    |:..:......|.....||:|||
Frog   320 NTQDQPIVLSIKKESQGISWESPIESIKVQESPPEPELKIEQSSCQIKVTFSDFVLHKMLGKGSF 384

  Fly   114 GEVFQVRDRSDGQLYAVKISKQ--LFRGEQYRAERLEE----VRRYEEFSGHENCIRFIRAWEQY 172
            |:||....:...|.:|:|:.|:  :...:......:|:    :.....|..|..|     .::..
Frog   385 GKVFLAELKRTNQFFAIKVLKKDVVLMDDDVECTMVEKRVLSLAWEHPFLTHLYC-----TFQTK 444

  Fly   173 DRLYMQME-LCRESLEQYLLRCQRIPEERIWHILLDLLRGLKSLHDRNLIHLDIKLDNVLIGEDD 236
            :.|:..|| |....|..::..|.:....|......:::.||:.||.:.:::.|:||||:|:..:.
Frog   445 EHLFFVMEYLNGGDLMFHIQSCHKFDLPRATFYAAEIVCGLQFLHSKGVVYRDLKLDNILLDMEG 509

  Fly   237 ETCKLADFGLVIDVDRANSHHATE-GDSRYMAPEILQGH-FSKAADIFSLGIAMLELACYMDLPS 299
            . .|:||||:..:....::..:|. |...|:|||||.|. ::.:.|.:|.|:.:.|:     |..
Frog   510 H-IKIADFGMCKESMLGDAKTSTFCGTPDYIAPEILLGQKYNYSVDWWSFGVLLYEM-----LIG 568

  Fly   300 NGPLWHELRHGILPEEFINKI-----------SLELQSVIKSMMKPDPAQRPTAE-QLLSHPKLQ 352
            ..|.     |||..||....|           |:|.:.::..:...:|.:|...: .:..|...|
Frog   569 QSPF-----HGIDEEELFQSIRMDNPMYPRFLSMEAKDILIMLFVREPERRLGVKGDIRQHCFFQ 628

  Fly   353 YLQKKRKSLMNFSMLSRSFRRSRRAVWGRMCN 384
            ::.                       |||:.|
Frog   629 HID-----------------------WGRLEN 637

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Myt1	NP_647987.2	PKc_Myt1	100..349	CDD:270952	64/269 (24%)
Myt1	NP_647987.2	Pkinase	102..349	CDD:278497	64/267 (24%)
prkcq	XP_012813823.2	C1_nPKC_theta-like_rpt1	150..210	CDD:410384
		C1_nPKC_theta-like_rpt2	229..278	CDD:410387
		STKc_nPKC_theta	367..697	CDD:270770	70/310 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910