Protein Alignment scny and UBP12

DIOPT Version :10

• Sequence 1: NP_729092.1
• Gene: scny / 38648
• FlyBaseID: FBgn0260936
• Length: 1038
• Species: Drosophila melanogaster
• Sequence 2: NP_012338.1
• Gene: UBP12 / 853242
• SGDID: S000003733
• Length: 1254
• Species: Saccharomyces cerevisiae
• Alignment Length: 1053
• Identity: 188/1053 - (17%)
• Similarity: 347/1053 - (32%)
• Gaps: 390/1053 - (37%)

  Fly   138 TSNPNELPKPKRVLYPRENIRIGWKQSERKWQVG-------------TGMINVGNTCYLNSTLQA 189
            ||||::|.           |.|...:....|...             ||::|:|||||:||.||.
Yeast   328 TSNPSDLV-----------IEIKPIEGNHHWPSNYFAYNKLEPASGTTGLVNLGNTCYMNSALQC 381

  Fly   190 LLHIPALANWL--------VSEQAHLADCNVAEPGSGCIICAMTKTLLATQSNQSAVRPFLIYSK 246
            |:|||.|.::.        ::|:..|............::..:.:..::.....:|..|.:..|.
Yeast   382 LVHIPQLRDYFLYDGYEDEINEENPLGYHGYVARAFSDLVQKLFQNRMSIMQRNAAFPPSMFKST 446

  Fly   247 LKQICKHMVVGRQEDAHEFLRFLVEAMERAYLMRFRNYKELDQLVKE------------------ 293
            :...........|:|:.|||.||::::          :::|::::|:
Yeast   447 IGHFNSMFSGYMQQDSQEFLAFLLDSL----------HEDLNRIIKKEYTEKPSLSPGDDVNDWN 501

  Fly   294 -----------------TTPLGQIFGGYLRSEVRCLSCNHVSITFQHFQDLLLDIRKADSLEDAF 341
                             .:.:..:|.|..:|.:.|..|.:|||||..:.|:.|.: ..|::.|
Yeast   502 VVKKLADDTWEMHLKRNCSVITDLFVGMYKSTLYCPECQNVSITFDPYNDVTLPL-PVDTVWD-- 563

  Fly   342 EGHFSRERLEDMGYKCEGCKKKVSATKQFSLERAPITLCIQLKRFSMIGNKLTKQISFKSRIDLS 406
                                   ...|.|.:...|:.|.::|.:.|             :.:||.
Yeast   564 -----------------------KTIKIFPMNSPPLLLEVELSKSS-------------TYMDLK 592

  Fly   407 KYAAR------------------------SQAAQAQPLTYRLVSMVTHLGASQHCGHYTAIGSTD 447
            .|..:                        |..:.||.||.:                 ..|...|
Yeast   593 NYVGKMSGLDPNTLFGCEIFSNQIYVNYESTESNAQFLTLQ-----------------ELIKPAD 640

  Fly   448 TGSFYNF----DDSYVRPIAMHSVCNT-------NAYI----MFFELDLSQAASPAANR----PN 493
            ...||..    |:..:.|     |.||       ||.:    .|..|...:..:|.|.|    ..
Yeast   641 DVIFYELPVTNDNEVIVP-----VLNTRIEKGYKNAMLFGVPFFITLKEDELNNPGAIRMKLQNR 700

  Fly   494 GVRLTNGHSTTPVPAATVSSPSPTRF------IGPQLPAGGANGYTNGNAQKTAI---------- 542
            .|.|:.|:...|.|..     :.|.|      :..:.|......|.: ..|.|:|
Yeast   701 FVHLSGGYIPFPEPVG-----NRTDFADAFPLLVEKYPDVEFEQYKD-ILQYTSIKVTDKDKSFF 759

  Fly   543 -----------QFKQQNQQSP-------QNGLQLGT---GKFQDTAKP-------------PLVG 573
                       ||...|:..|       |..|...|   .|.:|..|.             .|:.
Yeast   760 SIKILSVEKEQQFASNNRTGPNFWTPISQLNLDKATDIDDKLEDVVKDIYNYSSLVDCAEGVLMQ 824

  Fly   574 AHAKGEATSAPTANGNKSSSPSSNSSSNHKSINQQQYLPISSD-DEDIE--DEMKPRPTTAQLPS 635
            ...:|:...:...|.:|... |.:...|.:::...:.:..::| |||:|  |:::...:|.
Yeast   825 VDDEGDTEGSEAKNFSKPFQ-SGDDEENKETVTNNENVNNTNDRDEDMELTDDVEEDASTE---- 884

  Fly   636 MPNMTENHTEPKAKSPVKIQV-KTP---------VKTPLKSLVPYESASEEEEAPLPNPRKRPSG 690
             |.:|:   :|:|...:|..: .||         :......|...|:.|:::.....||...|:.
Yeast   885 -PELTD---KPEALDKIKDSLTSTPFAILSMNDIIVCEWSELGSNEAFSDDKIYNWENPATLPNK 945

  Fly   691 EDSSESDQESGQTNGHSKTNGSHTNGSASSSVHVNNSKQKTDAIDEIFKSLKKSADSDEDDDEEE 755
            |                         ..::.:..:|:|::|..:|:..:...|
Yeast   946 E-------------------------LENAKLERSNAKERTITLDDCLQLFSK------------ 973

  Fly   756 PSI-QLTNGWH-PQKQSQSQSKAPPSPKTPPSPAVIKSKTGIWKVTRNDEVDAIED----DVDV- 813
            |.| .||:.|: |..:...|:.........|...:|..|....:.:.:|::||..:    |:|:
Yeast   974 PEILGLTDSWYCPTCKEHRQATKQIQLWNTPDILLIHLKRFESQRSFSDKIDATVNFPITDLDLS 1038

  Fly   814 --VVVEGSP-------------------------VKIPTPNKNHRNPFSSSKPSTDSPATPGAKR 851
              ||.:..|                         ||....||.:.  |..|:.:..:|
Yeast  1039 RYVVYKDDPRGLIYDLYAVDNHYGGLGGGHYTAYVKNFADNKWYY--FDDSRVTETAP------- 1094

  Fly   852 QKLLNGSA-----LKSHQQPRVGNGYQSNATSNGSTINELLKQSYRGYGSPVLSWNGKPAEL--- 908
            :..:.|||     ::.|:.   |||..|      |.:.|::::|..||...:.....:..:|
Yeast  1095 ENSIAGSAYLLFYIRRHKD---GNGLGS------SKLQEIIQKSRHGYDERIKKIYDEQMKLYEF 1150

  Fly   909 -----EKEL---LVDAREQRQ-------------------RDIDDDEENEMDRGRQRKV------ 940
                 |:::   :::..|..|                   .|.||:::.|.....:||:
Yeast  1151 NKTDEEEDVSDDMIECNEDVQAPEYSNRSLEVGHIETQDCNDEDDNDDGERTNSGRRKLRLLKKV 1215

  Fly   941 -KSGSAKGNNASN 952
             |:.|..|:::::
Yeast  1216 YKNNSGLGSSSTS 1228

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scny	NP_729092.1	Peptidase_C19E	171..477	CDD:239126	70/400 (18%)
UBP12	NP_012338.1	UBP12	99..1111	CDD:227847	165/925 (18%)