DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment scny and UBP17

DIOPT Version :9

Sequence 1:	NP_729092.1	Gene:	scny / 38648	FlyBaseID:	FBgn0260936	Length:	1038	Species:	Drosophila melanogaster
Sequence 2:	NP_001332735.1	Gene:	UBP17 / 836670	AraportID:	AT5G65450	Length:	750	Species:	Arabidopsis thaliana

Alignment Length:	492	Identity:	135/492 - (27%)
Similarity:	217/492 - (44%)	Gaps:	57/492 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 NAALRESLGGNSSAGSSTDQAKSGEDTNGSLQNHIVANAKRILMAKIEYEEVPNYHESVLENLKS 79
            :|.||: ||..:|       .:||:..|.|:.:..::......|..:::|.:.:...|....:.|
plant   219 DAKLRK-LGNQNS-------RRSGDSANMSISDQFLSVGFEEEMNALKHERITSEPSSASAAMSS 275

  Fly    80 KYIVIKPGNPGAINGFSGKNNTGKLVGANGHDNNGARKQAEH--PNNQSHHINHHNHQHPTSNPN 142
            ...::.|....:....|..:::|.        ....:|..:|  |...|      ....|:|:.:
plant   276 SSTLLLPSKANSKPKVSQASSSGL--------KTSVQKVVQHFRPPQSS------KKSQPSSSID 326

  Fly   143 ELPKPKRV---LYPRENIRIGWKQSERKWQVGTGMINVGNTCYLNSTLQALLHIPALANWLVSEQ 204
            |:.....:   ||           .:|......|::|:||:||.|:.||.|.....|.::|: ..
plant   327 EMSFSYELFVKLY-----------CDRVELQPFGLVNLGNSCYANAVLQCLAFTRPLISYLI-RG 379

  Fly   205 AHLADCNVAEPGSGCIICAMTKTLLATQSNQSAVRPFLIYSKLKQICKHMVVGRQEDAHEFLRFL 269
            .|...|   ...|.|.:|.....:|..:..:|.:.|..|.|||::|.||:..|::||||||||..
plant   380 LHSKTC---RKKSWCFVCEFEHLILKARGGESPLSPIKILSKLQKIGKHLGPGKEEDAHEFLRCA 441

  Fly   270 VEAMERAYLMRFRNYKELDQLVKETTPLGQIFGGYLRSEVRCLSCNHVSITFQHFQDLLLDI-RK 333
            |:.|:..:|   :.........:|||.:|..|||||.|:::|::|.|.|...:...||.::| ..
plant   442 VDTMQSVFL---KEAPAAGPFAEETTLVGLTFGGYLHSKIKCMACLHKSERPELMMDLTVEIDGD 503

  Fly   334 ADSLEDAFEGHFSRERLE-DMGYKCEGCKKKVSATKQFSLERAPITLCIQLKRFSMIG-NKLTKQ 396
            ..|||:|.....:.|.|: :..|.|..||....|.|:..:...|..|.:.||||.... .||:|.
plant   504 IGSLEEALAQFTAYEVLDGENRYFCGRCKSYQKAKKKLMILEGPNILTVVLKRFQSDNFGKLSKP 568

  Fly   397 ISFKSRIDLSKYAARSQAAQAQPLTYRLVSMVTHLGA--SQHCGHYTAIGSTDTGSFYNFDDSYV 459
            |.|...:|:|.|  .|.........|.|.::|.||.|  :...|||.....|..|.::..|||.|
plant   569 IHFPELLDISPY--MSDPNHGDHPVYSLYAVVVHLDAMSTLFSGHYVCYIKTLDGDWFKIDDSNV 631

  Fly   460 RPIAMHSVCNTNAYIMFFELDLSQAASPAANRPNGVR 496
            .|:.:.:|....||::.:..|     ||.....||.|
plant   632 FPVQLETVLLEGAYMLLYARD-----SPRPVSKNGGR 663

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
scny	NP_729092.1	Peptidase_C19E	171..477	CDD:239126	102/310 (33%)
		UCH	172..477	CDD:278850	102/309 (33%)
		Asp-B-Hydro_N	<617..>731	CDD:191249
UBP17	NP_001332735.1	zf-MYND	76..113	CDD:396356
UBP17	NP_001332735.1	Peptidase_C19	349..650	CDD:351799	102/309 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	179	1.000	Domainoid score	I1057
eggNOG	1	0.900	-	-		E1_KOG1865
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000177
OrthoInspector	1	1.000	-	-		otm2471
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1006
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.810