Protein Alignment scny and USP5

DIOPT Version :10

• Sequence 1: NP_729092.1
• Gene: scny / 38648
• FlyBaseID: FBgn0260936
• Length: 1038
• Species: Drosophila melanogaster
• Sequence 2: NP_001092006.1
• Gene: USP5 / 8078
• HGNCID: 12628
• Length: 858
• Species: Homo sapiens
• Alignment Length: 305
• Identity: 59/305 - (19%)
• Similarity: 102/305 - (33%)
• Gaps: 92/305 - (30%)

  Fly   208 RVLDEELDSLDDDDEEIQFLRRMKMAKVVAVEEDVDDDEDRTRKHKKLSKVMKQNVEFPRGVGTS 272
            |:||:..|||.:..|.:..:..|...             |.|.|.|.|.|:.......|
Human   747 RLLDQNKDSLINFKEFVTGMSGMYHG-------------DLTEKLKALYKLHLPPALIP------ 792

  Fly   273 EKSAKKDKMGKAFDDADYVKDDDEEEEEAV-SDVEL-----------ENKSARTRRGAEEGQSEV 325
                  ::...|.:.|.|..:|...|...: ||::|           |.:..|.....:|.:.|.
Human   793 ------EEAESALEAAHYFPEDSSSEASPLASDLDLFLPWEAQAGLQEQQEGRGSEDIQERREEK 851

  Fly   326 KTE-------MTVTTRRRSGHSGNLIEFPRGLPPAPPRKRKENGLE-------------VDQQLK 370
            :|.       :.:..:.:......:.:.        |:..:|..:|             ::|.|.
Human   852 ETSPPDYRHYLRIWAKEKEAQKETIKDL--------PKMNQEQFIELCKTLYNMFSEDPLEQDLY 908

  Fly   371 KAEA-AQRRKLQVEKAARESEAEAIRKIL------GQDSSRKKKEDKIKKRQEDKAKE----KAA 424
            .|.| .....|::.:..::..|...:|..      ..:|:.::.|..|.|..:|.|:|    .|.
Human   909 HAIATVASLLLRIGEVGKKFSALTTKKPRDGAHSGDHNSATEEDEPPISKLHQDPARECQPPAAG 973

  Fly   425 DSIARRS----------DTVKWVMGPSGTIVTFPEELGLPSIFNS 459
            |..|:.|          |:...|.|.||      |..|.||:..|
Human   974 DPQAKASGDMHLGKALQDSHVIVEGGSG------EGQGSPSLLLS 1012

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scny	NP_729092.1	Peptidase_C19E	171..477	CDD:239126	59/305 (19%)
USP5	NP_001092006.1	zf-UBP_var	16..79	CDD:407678
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	74..96
		zf-UBP	199..272	CDD:460464
		Peptidase_C19B	327..854	CDD:239123	27/131 (21%)
		UBA1_UBP5	655..702	CDD:270566
		UBA2_UBP5	723..765	CDD:270569	7/17 (41%)