Protein Alignment scny and Usp1

DIOPT Version :10

• Sequence 1: NP_729092.1
• Gene: scny / 38648
• FlyBaseID: FBgn0260936
• Length: 1038
• Species: Drosophila melanogaster
• Sequence 2: NP_651687.3
• Gene: Usp1 / 43462
• FlyBaseID: FBgn0028476
• Length: 1078
• Species: Drosophila melanogaster
• Alignment Length: 767
• Identity: 153/767 - (19%)
• Similarity: 258/767 - (33%)
• Gaps: 187/767 - (24%)

  Fly    18 LRESLGGNSSAGSSTDQAKSG------EDTNGSLQNHIVANAKRILMAKIEYEEVPNYHESVLEN 76
            |..:|.||..| .||:...:.      :|.|.:.:.:...:|...||..:..  :...::|:::.
  Fly   426 LYNNLHGNEMA-DSTEPYHADTLLHAIQDVNATFEGNQQQDAHEFLMCVLNC--IRETNQSLIKA 487

  Fly    77 LKSKYIVIKPG---NPGAINGFSGKNNTGKLVGANGHDNNGARKQAEHPNNQSHHINHHNHQHPT 138
            :.....||..|   ||..::...|::.|......|.:..||:...::....:            |
  Fly   488 IGECPEVIANGYIANPDEVDTGEGQDRTDSTASQNLNAGNGSLATSQTTTTK------------T 540

  Fly   139 SNPNELPKPKRVLYPRENIRIGWKQSERKWQVGTGMINVGNTCYLNSTLQALLHIPALANWLVSE 203
            |..:...|.|..:.|.::.|:.....|.....| |:...|..   ::|..:|.::
  Fly   541 SFFSRKSKRKDEVKPSKSTRVQSPLKENSPTAG-GITGAGTA---HATANSLFYL---------- 591

  Fly   204 QAHLADCNVAEPGSGCIICAMTKTLLATQSNQSAVRPFLIYSKLKQICKHMVVGRQEDAHEFLRF 268
              :..|.:.|...||.          |:.|....|..........|..|:    ..:|.......
  Fly   592 --NTVDLSGASSTSGS----------ASTSASGVVSTSAALPTPPQATKY----SSDDEMNSATV 640

  Fly   269 LVEAMERAYLMRFRNYKELDQLVKETTP--LGQIFGGYLRSEVRCLSCNHVSITFQHFQDLLLDI 331
            |.:.|            .|::.::|...  ....|.|.:....:||||..::...|...|:.:.:
  Fly   641 LKDKM------------RLEERIRELNLNFFSSDFEGIVVLTTKCLSCETITRQKQGMLDISVPV 693

  Fly   332 -----RKADSLEDA--------------FEGHFSRERLEDMGYKCEGCKKKVSATKQFSLERAPI 377
                 ..|| |:|.              |.|        :..|.|..|.....|.:..|.|..|.
  Fly   694 PISGYDNAD-LQDKPSTYIQNSCITKEYFRG--------ENKYSCNQCTGYTEAIRSISYEVLPR 749

  Fly   378 TLCIQLKRFSMIGNKLTKQISFKSRIDLSKYAAR-SQAAQAQPL-TYRLVSMVTHLGASQHCGHY 440
            .|.|||.|||....|::..:  .:...|..:.|. .:..:...| .|:|.|::||:||:...|||
  Fly   750 LLVIQLNRFSGGMEKVSTYV--PTTFTLPCFCATCCELGEGNKLHVYKLYSVITHVGATLTVGHY 812

  Fly   441 TAIGSTDTGSFYNFDDSYVRPIAMHSVCNTNAYIMFFELDLSQAASPAAN-RPNGVRLTNGHS-- 502
            .|.     ..|.:....||..........||:..|     .|||.....| .||     ||.|
  Fly   813 IAY-----TCFLDLASDYVNCPKDRRNTMTNSQTM-----ASQAVPSNENAAPN-----NGSSSV 862

  Fly   503 -TTPVPAATVSSPSPTRFIGPQLPAGGANGYTNGNAQKTAIQFKQQNQQSPQNGLQLGTGKFQDT 566
             :|||.||..:..|....:..::..|.:...::|:..|..   ||.|....:| :..|.||...:
  Fly   863 ASTPVIAAASALASSGNILMKKMKFGRSKASSSGDMSKNV---KQVNGIISKN-ITNGIGKLSIS 923

  Fly   567 AKPPLVGAHAKGEATSAPTANGNKSS-------SPSSNSSSN----------------------- 601
            .....|...|.....:..|::.|.:|       |..:.|:||
  Fly   924 TTCQGVNCCAMRLCCTQQTSSSNSTSCSDFSEESLQNGSNSNLSFGGSGSTYPTGYGSTGRGGVR 988

  Fly   602 ----HKSINQQQYLPISSDDEDIEDEMKPRPTTAQLPSMPNMTENHTEPKAKSPVKIQVKTPVKT 662
                |...:...|:   .||:.|:                .||:...|.......||.:     |
  Fly   989 ANYAHGGPDPIWYM---CDDDKIK----------------AMTQREFEELLSPTRKITI-----T 1029

  Fly   663 P-LKSLVPYESASEEEEAPLPNPRKRPSGEDSSESDQESGQTNGHSKTNGSH 713
            | |.....::...::...|:|.....|....|::|     ..:..:.::|||
  Fly  1030 PYLLFYARFDLQPQKATPPMPGSSTTPPPPSSAQS-----SWSNENVSSGSH 1076

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scny	NP_729092.1	Peptidase_C19E	171..477	CDD:239126	68/328 (21%)
Usp1	NP_651687.3	Peptidase_C19	308..819	CDD:470612	92/465 (20%)