DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment scny and not

DIOPT Version :9

Sequence 1:NP_729092.1 Gene:scny / 38648 FlyBaseID:FBgn0260936 Length:1038 Species:Drosophila melanogaster
Sequence 2:NP_001287106.1 Gene:not / 40030 FlyBaseID:FBgn0013717 Length:496 Species:Drosophila melanogaster


Alignment Length:371 Identity:93/371 - (25%)
Similarity:166/371 - (44%) Gaps:69/371 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   148 KRVLYPRENIRIGWKQSERKWQVGTGMINVGNTCYLNSTLQALLHIPALANWLVSEQAHLADCNV 212
            :|::.|.:.|.:            .|::|:|.||::|..:|||:|.|.|:::.:|:: |  ||. 
  Fly   146 RRLVRPNQTIGL------------RGLLNLGATCFMNCIVQALVHTPLLSDYFMSDR-H--DCG- 194

  Fly   213 AEPGSGCIICAMTKTLLATQSNQSAVRPFLIYSKLKQI---CKHMVVGRQEDAHEFLRFLVEAME 274
            ::....|::|.:::......|...:  |..::..|..|   .||:....|:|||||....::.:.
  Fly   195 SKSSHKCLVCEVSRLFQEFYSGSRS--PLSLHRLLHLIWNHAKHLAGYEQQDAHEFFIATLDVLH 257

  Fly   275 RAYLMRFRNYKELDQLVKETTP-----------------------LGQIFGGYLRSEVRCLSCNH 316
            |..:.....::.     |..:.                       :.|||.|.|:|:|.|.:||.
  Fly   258 RHCVKAKAEHES-----KSNSSGSGSGTNSSNSSSSHCYGQCNCIIDQIFTGMLQSDVVCQACNG 317

  Fly   317 VSITFQHFQDLLLDIRKA--------DSLEDAFEGHFSRERLEDMG----YKCEGCKKKVSATKQ 369
            ||.|:..|.|:.||:.:.        .:|.|..|.:   .|.|.:|    .||..||....:|||
  Fly   318 VSTTYDPFWDISLDLGETTTHGGVTPKTLIDCLERY---TRAEHLGSAAKIKCSTCKSYQESTKQ 379

  Fly   370 FSLERAPITLCIQLKRF---SMIGNKLTKQISFKSRIDLSKYAARSQAAQAQPLTYRLVSMVTHL 431
            |||...|..:...||||   ::|..|::..|.|....|::.:.:..:.|... ..:.|.::|.|:
  Fly   380 FSLRTLPSVVSFHLKRFEHSALIDRKISSFIQFPVEFDMTPFMSEKKNAYGD-FRFSLYAVVNHV 443

  Fly   432 GASQHCGHYTAIGSTDTGSFYNFDDSYVRPIAMHSVCNTNAYIMFF 477
            |... .|||||.......::...||..:...::..|.::..|::|:
  Fly   444 GTID-TGHYTAYVRHQKDTWVKCDDHVITMASLKQVLDSEGYLLFY 488

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
scnyNP_729092.1 Peptidase_C19E 171..477 CDD:239126 89/346 (26%)
UCH 172..477 CDD:278850 89/345 (26%)
Asp-B-Hydro_N <617..>731 CDD:191249
notNP_001287106.1 zf-UBP 46..103 CDD:307999
Peptidase_C19D 158..489 CDD:239125 90/347 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45456858
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.840

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