Protein Alignment scny and USP50

DIOPT Version :10

• Sequence 1: NP_729092.1
• Gene: scny / 38648
• FlyBaseID: FBgn0260936
• Length: 1038
• Species: Drosophila melanogaster
• Sequence 2: NP_987090.2
• Gene: USP50 / 373509
• HGNCID: 20079
• Length: 334
• Species: Homo sapiens
• Alignment Length: 292
• Identity: 78/292 - (26%)
• Similarity: 125/292 - (42%)
• Gaps: 31/292 - (10%)

  Fly   172 TGMINVGNTCYLNSTLQALLHIPALANWLVSEQAHLA---DCNVAEPGSGCIICAMTKTLLATQS 233
            ||:.|:||||.:|:..|.|..|..|..:.::.:...|   ||:........:   ||...|   .
Human    44 TGLWNLGNTCCVNAISQCLCSILPLVEYFLTGKYITALQNDCSEVATAFAYL---MTDMWL---G 102

  Fly   234 NQSAVRPFLIYSKLKQICKHMVVGRQEDAHEF----LRFLVEAMERAYLMRFRNYKE-------L 287
            :...|.|.:.:|.|..:........|:||.||    |..|.||:::.:..|.|:|::       .
Human   103 DSDCVSPEIFWSALGNLYPAFTKKMQQDAQEFLICVLNELHEALKKYHYSRRRSYEKGSTQRCCR 167

  Fly   288 DQLVKETTPLGQIFGGYLRSEVRCLSCNHVSITFQHFQDLLLDI--RKADSLEDAFEGHFSRERL 350
            ..:..||:.:.|:|...|...:.||.|...:...:.|....|.|  :...||.|..:..|.::.|
Human   168 KWITTETSIITQLFEEQLNYSIVCLKCEKCTYKNEVFTVFSLPIPSKYECSLRDCLQCFFQQDAL 232

  Fly   351 E-DMGYKCEGCKKKVSATKQFSLERAPITLCIQLKRFSMIG---NKLTKQISFK-SRIDLSKYAA 410
            . :....|..|:.|.....:.|:.:||..:...||||.:.|   .||...|.:. :.:||:.|..
Human   233 TWNNEIHCSFCETKQETAVRASISKAPKIIIFHLKRFDIQGTTKRKLRTDIHYPLTNLDLTPYIC 297

  Fly   411 RSQAAQAQPLTYRLVSMVTHLGASQHCGHYTA 442
              ...:..| .|.|.::|.|.| ....|||||
Human   298 --SIFRKYP-KYNLCAVVNHFG-DLDGGHYTA 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scny	NP_729092.1	Peptidase_C19E	171..477	CDD:239126	78/292 (27%)
USP50	NP_987090.2	UCH	44..329	CDD:425685	78/292 (27%)