DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment scny and DUBAI

DIOPT Version :9

Sequence 1:	NP_729092.1	Gene:	scny / 38648	FlyBaseID:	FBgn0260936	Length:	1038	Species:	Drosophila melanogaster
Sequence 2:	NP_610784.1	Gene:	DUBAI / 36361	FlyBaseID:	FBgn0033738	Length:	852	Species:	Drosophila melanogaster

Alignment Length:	555	Identity:	124/555 - (22%)
Similarity:	205/555 - (36%)	Gaps:	166/555 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   145 PKPKRVLYPR---ENIRIGWKQSERKWQVGTGMINVGNTCYLNSTLQALLHIPALANWLVSEQAH 206
            |.|..|...:   ||.:...:::.|     .|::|:|||||:||.||||    |:.:.. |.|..
  Fly   333 PSPNCVALAKAMHENAQPWGRRNAR-----VGLVNLGNTCYMNSVLQAL----AMTSDF-SRQIL 387

  Fly   207 LADCNVAEPGSGCIICAMTKTLLATQSNQSAVRPFLIYSKLKQICKHMVVGRQEDAHEFLRFLVE 271
            |.:||     |..::....:..|...|.:..:.|..:.:..:.  .....|.|:|:.|||.:|::
  Fly   388 LIECN-----SVLLMKVQQQIALMHHSLRYELTPSRVLNATRP--PSFTPGLQQDSSEFLGYLLD 445

  Fly   272 AMERAYLMRFR--------------------------------------------------NYK- 285
            .:....:....                                                  |:|
  Fly   446 LLHEHEINSSSVTGHSVGPPKTGREVDDVPALLSEDILSSGVIPYNSKDHELSSGSNSDNCNHKP 510

  Fly   286 --------------------ELDQLVKETTPLGQIFGGYLRSEVRCLSCNHVSITFQHFQDLLLD 330
                                ::|| .|..:.:.:.|.|.|.:..|||:|...|.....|::|.|.
  Fly   511 TPTPPATPTKATNGLKQQGQQVDQ-AKPPSTIDKTFAGKLSTTYRCLNCGWESRNEDSFRELQLS 574

  Fly   331 I--RKAD------SLEDAFEGHFSRERLE-DMGYKCEGCKKKVSATKQFSLERAPITLCIQLKRF 386
            .  .|.|      |::|..|.:.|.|:|: |..|.|..|||...|.:...:.:||..|.:.||:|
  Fly   575 FPDDKEDCGATNYSVQDLIEYYCSPEKLDGDNQYFCPQCKKLCDAERHIGVTQAPKNLILTLKQF 639

  Fly   387 SMIGNKLTKQISFKSRI------DLS---KYAARSQAAQAQPLTYRLVSMVTHLGASQHCGHYTA 442
                 |..::..|::::      |.|   |.:|:....:...:.|.|.:.|.|.|.|...|||..
  Fly   640 -----KYDQKYHFRTKLMHKVFHDESVTVKMSAKDSLQEMSTVHYDLYAGVVHAGYSMDSGHYFT 699

  Fly   443 IGSTDTGSFYNFDDSYV---RPIAMHSVCNTNA-YIMFFEL------DLSQAASPAANRPNGVRL 497
            ..:....::|.|:|:.|   :|..||::.:.|. ||:|:::      ..|..||.:::..:|
  Fly   700 FAADQAKNWYKFNDNVVTHSKPEEMHNLTSPNTPYILFYKMCGHSNESNSVTASCSSSMVSG--- 761

  Fly   498 TNGHSTTPVPAATVSSP-----SPTRF--------------IGPQLPAGGANGYTNGNAQKTAIQ 543
                |...|.:..:|.|     .|.|.              :..|....|.:|:  |||..:...
  Fly   762 ----SNDQVVSVPLSPPLKLEELPRRLRDYVRKDNHVYNEELKMQRFKRGNSGH--GNAFVSRHN 820

  Fly   544 FKQQNQQSPQNGLQLGTGKFQDTAKPPLVGAHAKG 578
            |.             |.|...|.|.||..|....|
  Fly   821 FD-------------GDGDEDDKAPPPPGGCGGNG 842

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
scny	NP_729092.1	Peptidase_C19E	171..477	CDD:239126	92/398 (23%)
		UCH	172..477	CDD:278850	92/397 (23%)
		Asp-B-Hydro_N	<617..>731	CDD:191249
DUBAI	NP_610784.1	UCH	358..738	CDD:278850	92/397 (23%)
DUBAI	NP_610784.1	Peptidase_C19H	359..739	CDD:239129	93/397 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468761
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24006
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940