DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment scny and Usp14

DIOPT Version :9

Sequence 1:	NP_729092.1	Gene:	scny / 38648	FlyBaseID:	FBgn0260936	Length:	1038	Species:	Drosophila melanogaster
Sequence 2:	NP_001260321.1	Gene:	Usp14 / 34387	FlyBaseID:	FBgn0032216	Length:	475	Species:	Drosophila melanogaster

Alignment Length:	381	Identity:	77/381 - (20%)
Similarity:	145/381 - (38%)	Gaps:	94/381 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   173 GMINVGNTCYLNSTLQALLHIPALANWLVSEQAHLADCNVAEPGSGCIICAMTKTLLATQSNQSA 237
            |:.|:|||||:|:|:|.|..:|.|...|    :..::.......:...|.:..|::.|.....:.
  Fly   105 GLTNLGNTCYMNATVQCLNAVPELRTAL----STFSNDGTDTMSTAFSISSAMKSIFAQMEKGTT 165

  Fly   238 VRPFLIYSKLKQICKHMV------VGRQEDAHEFLRFLVEAMERAYLMRFRNYKELDQLVK-ETT 295
            |.|.::...|.:......      ..||:||:|....:::.:::.  :|.:|.:..:.:.| .::
  Fly   166 VTPIVLLQALHRASPQFAQTGENGTYRQQDANECWAEILKMLQQK--LRPKNQEPSNTVQKRHSS 228

  Fly   296 PLGQIFGGYLRSEVRCLS----CNHVSITFQHFQDL----LLDIRKADSLEDAFEGHFSRERLED 352
            .:.|.|||..  ||:..|    ....::|.::|..|    .:|::...|      |..|:.: |.
  Fly   229 FIDQFFGGTF--EVKMSSEEDPDEPSTVTSENFLQLSCFISMDVKYMQS------GLKSKMK-EQ 284

  Fly   353 MGYKCEGCKKKVSATKQFSLERAPITLCIQLKRFSMIGN-----KLTKQISF------------- 399
            :..|.|...:.....:.:.:.|.|..|.:|..||...|.     |:.|.|.|
  Fly   285 LVKKSETLGRDAKYIRTYLVSRLPAYLTVQFVRFQYKGKEGINAKVLKDIKFPIDFDAFELCTPE 349

  Fly   400 ------------------KSRIDLSKYAARSQAAQAQPLT------------------YRLVSMV 428
                              |..:|:.|   |::..:.:...                  |.|.:::
  Fly   350 LQNKLCPMRSKFKDLEDKKMEVDVVK---RNEPNEEKKDVKYEQFWFDDDLGSNNSGYYTLQAVL 411

  Fly   429 THLGASQHCGHYTAIGSTDTGSFYNFDDSYVRPIAMHSVCNTN-------AYIMFF 477
            ||.|.|...|||.|...:....::.|||..|..:|...:...:       ||::.:
  Fly   412 THKGRSSSSGHYVAWVRSSGDVWFKFDDDEVSAVATDEILRLSGGGDWHCAYVLLY 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
scny	NP_729092.1	Peptidase_C19E	171..477	CDD:239126	77/379 (20%)
		UCH	172..477	CDD:278850	77/379 (20%)
		Asp-B-Hydro_N	<617..>731	CDD:191249
Usp14	NP_001260321.1	UBQ	4..73	CDD:214563
		UBQ	5..73	CDD:294102
		UCH	103..467	CDD:278850	77/379 (20%)
		Peptidase_C19A	105..467	CDD:239122	77/379 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456878
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930