Protein Alignment scny and Usp36

DIOPT Version :10

• Sequence 1: NP_729092.1
• Gene: scny / 38648
• FlyBaseID: FBgn0260936
• Length: 1038
• Species: Drosophila melanogaster
• Sequence 2: NP_001100539.2
• Gene: Usp36 / 303700
• RGDID: 1309937
• Length: 1098
• Species: Rattus norvegicus
• Alignment Length: 1135
• Identity: 277/1135 - (24%)
• Similarity: 463/1135 - (40%)
• Gaps: 269/1135 - (23%)

  Fly    37 SGEDTNGSLQNHIVANAKRILMAKIEYEEVPNYHESVLENLKSKYIVIKPGNPGAINGFSGKNNT 101
            |.||  |.|...:.|:||::|:.:||:|.........||:|||||:::.|...||
  Rat    18 SAED--GDLGKLLAASAKKVLLQRIEFEPASKSFSYQLESLKSKYVLLNPKAEGA---------- 70

  Fly   102 GKLVGANGHDNNGARKQAEHPNNQSHHINHHNHQHPTSNPNELPKPKRVLYPRENIRIGWKQSER 166
                   |...:|...||..|..:         :...|..:.:|.|::||:|.|.:.:.|   ||
  Rat    71 -------GRHRSGDEPQARKPGTE---------RMSGSGGDGVPAPQKVLFPVERLSLRW---ER 116

  Fly   167 KWQVGTGMINVGNTCYLNSTLQALLHIPALANWLVSEQAHLADCNVAEPGSGCIICAMTKTLLAT 231
            .::||.|:.|:||||:||||:|.|.:.|.|||:|:|:: |...|:   .||.|::|.|...::..
  Rat   117 VFRVGAGLHNLGNTCFLNSTIQCLTYTPPLANYLLSKE-HARSCH---QGSFCMLCVMQNHMVQA 177

  Fly   232 QSNQ-SAVRPFLIYSKLKQICKHMVVGRQEDAHEFLRFLVEAMERAYLMRFRNYKELDQLVKETT 295
            .:|. :|::|......||:|.:|...|.|||||||||:.::||::|.|   ..|.:||:..:.||
  Rat   178 FANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYTIDAMQKACL---NGYAKLDRQTQATT 239

  Fly   296 PLGQIFGGYLRSEVRCLSCNHVSITFQHFQDLLLDIRKADSLEDAFEGHFSRERLE-DMGYKCEG 359
            .:.|||||||||.|:|..|..||.|:..:.|:.|:||:|.::..|.|.....:.|. :..|.|..
  Rat   240 LVHQIFGGYLRSRVKCSVCRSVSDTYDPYLDIALEIRQAANIVRALELFVKSDVLSGENAYMCAK 304

  Fly   360 CKKKVSATKQFSLERAPITLCIQLKRF-SMIGNKLTKQISFKSRIDLSKYAARSQAAQAQPLTYR 423
            |||||.|:|:||:.|....|.:.|||| :..|.|:||.:.:...:::..|.::|   ...|:.|.
  Rat   305 CKKKVPASKRFSIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFLNIRPYMSQS---SGDPVMYG 366

  Fly   424 LVSMVTHLGASQHCGHYTAIGSTDTGSFYNFDDSYVRPIAMHSVCNTNAYIMFF----------E 478
            |.:::.|.|.|.|.|||........|.:|..:||.|....:..|.:..||::|:          |
  Rat   367 LYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNVKVVLSQQAYVLFYLRIPGSKKSPE 431

  Fly   479 LDLSQAASPAANRP-------------------------------------------------NG 494
            ..:|:..:...:||                                                 :|
  Rat   432 GPVSRVGATLPSRPKVIPEHPKKSPGNGVVSSPLMAKRQDSLMMRKLQSPEEVGMPVSRNGSISG 496

  Fly   495 VRLTNGHSTTPVPAATVS---SPSPTRFIGPQL---PAGGANGYTNGNAQKTAIQFKQQNQQSPQ 553
            ::|.||.:....||.:.|   :|:||..  |.:   |        ....:|:|....:....:..
  Rat   497 LKLQNGCAPAKSPAGSPSPRLAPTPTHM--PTILDEP--------GEKVKKSAPPQSRTTSPTAS 551

  Fly   554 NGLQLGTGKFQD-------------TAKPPLV-----GAHAKGEATSAPTANGNKSSSPSSNSSS 600
            .|.. |||:.:.             :..|.|.     |...|||........|:.|||...:|:|
  Rat   552 QGFP-GTGESRSQRPGSWASRDSIFSTSPKLAKAITNGHRLKGEGNGVDLEKGDSSSSSPEHSAS 615

  Fly   601 N--------------HKSINQQQYLPISSDDEDIEDEMKPRPTTAQLPSMPNMTENHTEPKAKSP 651
            :              |...:|....|.:...:.:.:.:..:....:.|::.:.|...|...:..|
  Rat   616 SDAAKAPQTSEGRAAHVCDSQGTNCPATGHSKVLSNGVDAKMGKLKSPALSSTTTEPTSLMSPPP 680

  Fly   652 VK-------------------IQVKTP-----VKTPLKSLVPY------ESASEEEEAPLPNPRK 686
            .|                   |...:|     :.:|:|:..|.      .|.:....||.|.|..
  Rat   681 AKKLALSAKKASTLRRATGNDIGSPSPSAFCDLTSPMKATHPVVASPGPVSKTRAAAAPAPQPSP 745

  Fly   687 RP-SGEDSSESDQESGQTNGHSKTNGSHT-----NGSASSSVHVNNSKQKTDAIDEIFKSLKKSA 745
            .| |...||.|.:..|.:...|..:.:.|     ||..:|  |::...:..:|:....:..||:.
  Rat   746 HPHSASLSSSSAKPLGTSEPQSCCSSAWTPLPQVNGHFTS--HLHQLPEANEALHSPSRKRKKTP 808

  Fly   746 DSD----------------------EDDDEEEPSIQLTNGWHPQKQSQSQSKAPPSPKTPPSPAV 788
            ..|                      ....:::..::.......|::||||.: |.||:.
  Rat   809 SGDPQRLGRDTHLPQCLEGAPATARRKKRKKKKDLEGVGDTATQQESQSQDQ-PWSPRG------ 866

  Fly   789 IKSKTGIWKVTRNDEVDAIEDDV------------------------DVVVVEGSPVKIPTP--- 826
             :.:.|........:|..|.|..                        |::....||.....|
  Rat   867 -RKEEGTQLQVNGHQVSHILDSYHASSRKRRKRKRSEGLSQEATVCQDLLQHGCSPADHCEPEAR 930

  Fly   827 -------NKNHRNPFSSSKPSTDSPATPGAKRQKL--LNGSALKSH-QQPRVGNGYQSNATSN-- 879
                   .:..|.|....:..::.|....:.|..:  :....:..| ...|:|.|.....|.|
  Rat   931 TELQKKKKRRKRKPEPQQEEESEHPGYQRSPRPSVTPVPELCVNDHLPSDRLGLGRAPLVTWNRD 995

  Fly   880 --GSTINELLKQSY-RGYGSPVLSWNGKPAELEKELLVDAREQRQRDIDDDEENEMDRGRQRKVK 941
              ...:.|||:.|. ..||..||:|:|:|:.:.::.:.|:|..|.:.:.||.:.|.|||:::|:|
  Rat   996 QEPDVVQELLQDSSDTAYGKKVLTWDGEPSAISQDAMKDSRLARTQTVVDDWDEEFDRGKEKKIK 1060

  Fly   942 SGSAKGNNASNSTPGYNPFQEYEGQKR-WN 970
              ..|.....|    :|.||:.:.::. |:
  Rat  1061 --KFKREKKRN----FNAFQKLQSRRNFWS 1084

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scny	NP_729092.1	Peptidase_C19E	171..477	CDD:239126	116/308 (38%)
Usp36	NP_001100539.2	None