DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment scny and ubp3

DIOPT Version :9

Sequence 1:	NP_729092.1	Gene:	scny / 38648	FlyBaseID:	FBgn0260936	Length:	1038	Species:	Drosophila melanogaster
Sequence 2:	NP_596528.1	Gene:	ubp3 / 2541378	PomBaseID:	SPBP8B7.21	Length:	512	Species:	Schizosaccharomyces pombe

Alignment Length:	459	Identity:	111/459 - (24%)
Similarity:	177/459 - (38%)	Gaps:	127/459 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   115 ARK--QAEHPNNQSHHI----NHHNHQHPTSNPNEL----------PKPKRVLYPRENIRIGWKQ 163
            |:|  |.:.|..:||.:    :....:...|:..||          |:|   :.||
pombe    81 AKKHVQGDSPVKKSHSVPVPSDRSEKKSFNSSLGELIETYSPSLDAPRP---IQPR--------- 133

  Fly   164 SERKWQVGTGMINVGNTCYLNSTLQALLHIPALANWLVSEQAHLADCNVAEPGSGCIICAMTKTL 228
                     |.||.||.|::||.||||::.....| |:.:...:...|. |..:..|   .:.|:
pombe   134 ---------GFINTGNICFMNSILQALMYCVPFYN-LLKQINRMVPYNF-ERTTPLI---ESLTM 184

  Fly   229 LATQSNQ---------SAVRPFLIYSKLK--QICKHMVVGRQEDAHEFLRFLVEAMERAYLMRFR 282
            |:....:         .::.|.::||..|  ...:.:..|.||||.|||...::.:...::...|
pombe   185 LSRDFREYSEKFDLQGDSILPEVVYSATKGNPRFEMLQTGEQEDAEEFLNLFLDELHEEFVRERR 249

  Fly   283 NY--------------------KELDQL--------------------------VKETTPLGQIF 301
            :|                    ..||..                          ..|.:|:.|||
pombe   250 HYLLKNDERNPKSDIKISNGIKSGLDSFDDQSSVEASGWTEVGKNKKPVIARSATVERSPISQIF 314

  Fly   302 GGYLRSEVRCLSCNHVSITFQHFQDLLLDIRKAD--SLEDAFEGHFSRERLEDMGYKCEGCKKKV 364
            ||.|||.:|..|... |:..:.||.|.|||:..|  |:.||.|...:.|.|.:.    ...|..|
pombe   315 GGQLRSTLRVPSARD-SVLLEPFQPLQLDIQAEDIHSVIDALEHMTAPEILPEW----HSSKGNV 374

  Fly   365 SATKQFSLERAPITLCIQLKRF----SMIGNKLTKQISFKSRIDLSKYAARSQAAQAQPLTYRLV 425
            :||||..:|..|..|.:.||||    |....|..|.|::.:|:.:.:.........:....|.|.
pombe   375 TATKQMYIESLPPVLILHLKRFFYEASGGTQKNYKPIAYPARLSIPQNVFSPSVRGSIHPEYDLN 439

  Fly   426 SMVTHLGASQHCGHYTA-IGSTDTGSFYNFDDSYVRPIAMHSVCNTN----------------AY 473
            ::|.|.|.|...||||. :...|...::..||:::..:.:|.|.|:.                ||
pombe   440 AVVYHHGTSASGGHYTVDVQQLDKSGWFRIDDTHIHRVPIHDVENSELSADPSLSKLGHGDRVAY 504

  Fly   474 IMFF 477
            ::|:
pombe   505 LLFY 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
scny	NP_729092.1	Peptidase_C19E	171..477	CDD:239126	97/385 (25%)
		UCH	172..477	CDD:278850	97/384 (25%)
		Asp-B-Hydro_N	<617..>731	CDD:191249
ubp3	NP_596528.1	UCH	132..508	CDD:278850	99/403 (25%)
ubp3	NP_596528.1	Peptidase_C19	134..508	CDD:239072	97/383 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	2	1.870