DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment scny and Usp3

DIOPT Version :9

Sequence 1:	NP_729092.1	Gene:	scny / 38648	FlyBaseID:	FBgn0260936	Length:	1038	Species:	Drosophila melanogaster
Sequence 2:	XP_006511173.1	Gene:	Usp3 / 235441	MGIID:	2152450	Length:	606	Species:	Mus musculus

Alignment Length:	358	Identity:	105/358 - (29%)
Similarity:	164/358 - (45%)	Gaps:	60/358 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   172 TGMINVGNTCYLNSTLQALLHI----------PAL-------ANWLVSEQAHLADCNVAEPGSGC 219
            ||:.|:||||::|:.||:|.:|          ||:       |...........|.||:
Mouse   245 TGLRNLGNTCFMNAILQSLSNIEQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDSNVS------ 303

  Fly   220 IICAMTKTLLAT-QSNQSAVRPFLIYSKLKQICKHMVVGRQEDAHEFLRFLVEAMERAYLMRFRN 283
            ::....|||.|. |.:|:|..|..::..:.:|..:....:|:|||||:|:|::.:.......| |
Mouse   304 LVEEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGF-N 367

  Fly   284 YKELDQLVKETTPLG---------------QIFGGYLRSEVRCLSCNHVSITFQHFQDLLLDI-- 331
            ......:::|.:.|.               .||||.|::||.||.|...|..|..|.||.|||
Mouse   368 GVSRSAILQENSTLSASNKCCINGASTVVTAIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPS 432

  Fly   332 -----RKAD-------SLEDAFEGHFSRERLEDMG-YKCEGCKKKVSATKQFSLERAPITLCIQL 383
                 |..:       ||.|........|.|::.. |.|..||||..:||:|.:::.|..||:.|
Mouse   433 QFRSKRSKNQENGPVCSLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKALCLHL 497

  Fly   384 KRF---SMIGNKLTKQISFKSR-IDLSKYAARSQAAQAQPLTYRLVSMVTHLGASQHCGHYTAIG 444
            |||   :.:.||:...:.|..| :|:..|....:.:......|.|.::|.|.|:....|||||.
Mouse   498 KRFHWTAYLRNKVDTYVQFPLRGLDMKCYLLEPENSGPDSCLYDLAAVVVHHGSGVGSGHYTAY- 561

  Fly   445 STDTGSFYNFDDSYVRPIAMHSVCNTNAYIMFF 477
            :...|.:::|:||.|......:|....|||:|:
Mouse   562 AVHEGRWFHFNDSTVTVTDEETVGKAKAYILFY 594

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
scny	NP_729092.1	Peptidase_C19E	171..477	CDD:239126	104/356 (29%)
		UCH	172..477	CDD:278850	104/356 (29%)
		Asp-B-Hydro_N	<617..>731	CDD:191249
Usp3	XP_006511173.1	zf-UBP	117..191	CDD:366940
Usp3	XP_006511173.1	UCH	245..594	CDD:366104	104/356 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	2	1.870