Protein Alignment scny and Usp10

DIOPT Version :10

• Sequence 1: NP_729092.1
• Gene: scny / 38648
• FlyBaseID: FBgn0260936
• Length: 1038
• Species: Drosophila melanogaster
• Sequence 2: XP_006530908.1
• Gene: Usp10 / 22224
• MGIID: 894652
• Length: 818
• Species: Mus musculus
• Alignment Length: 659
• Identity: 149/659 - (22%)
• Similarity: 231/659 - (35%)
• Gaps: 246/659 - (37%)

  Fly     2 PVSMAVCETAN---------VVNAALRESLGGNS-SAG----------------------SSTDQ 34
            ||....|::..         |.::....:|||:: :||                      ::..|
Mouse   226 PVMPRTCDSPQNPVDFISGPVPDSPFPRTLGGDARTAGLCEGCHEADFEQPCLPADSLLRTAGTQ 290

  Fly    35 AKSGEDTNGSLQNHIVANAKRILMAKIEYEEVPNYHESVLENLKSKYIVIKPGNPGAINGFSGKN 99
            ...|.||.   :|..|||.|                  :||:         ||...|.|
Mouse   291 PYVGTDTT---ENFAVANGK------------------ILES---------PGEDTAAN------ 319

  Fly   100 NTGKLVGANGHDNNGARKQAEHPNNQSHHIN---------------------HHNHQHPTSNP-- 141
                  ||..|.:.||......|.:||....                     .|:.:...|:|
Mouse   320 ------GAELHTDEGADLDPAKPESQSPPAESALSASGAIPISQPAKSWASLFHDSKPSASSPMA 378

  Fly   142 -------NELPKP---------KRVLYPRENIRIGWKQSERKWQV----------GTGMINVGNT 180
                   ..:|.|         |..|.|.....:..|.:|....|          ..|:||.||.
Mouse   379 YVETKCSPPVPSPLASEKQMEVKEGLVPVSEDPVAIKIAELLETVTLIHKPVSLQPRGLINKGNW 443

  Fly   181 CYLNSTLQALLHIPALANWLVSEQAHLAD-----CNVAEPGSGCIICAMTKTLLATQSN------ 234
            ||:|:|||||:..|.:        .||..     ..|..|   |....|..:.:...:.
Mouse   444 CYINATLQALVACPPM--------YHLMKFIPLYSKVQRP---CTSTPMIDSFVRLMNEFTNMPV 497

  Fly   235 ------------------QSAVRPFLIYSKLKQICKHMV--VGRQEDAHEFLRFLVEAMERAYLM 279
                              .:|..|..|| :|..:.|..:  .||||||.|:|.|::..:....|
Mouse   498 PPKPRQALGDKIVRDIRPGAAFEPTYIY-RLLTVIKSSLSEKGRQEDAEEYLGFILNGLHEEML- 560

  Fly   280 RFRNYKEL--------------------DQLVKET---------------------------TPL 297
               :.|:|                    |:.:::|                           ||:
Mouse   561 ---SLKKLLSPTHEKHSVSNGPRSDLIEDEELEDTGKGSEDEWEQVGPKNKTSITRQADFVQTPI 622

  Fly   298 GQIFGGYLRSEVRCLSCNHVSITFQHFQDLLLDIR--KADSLEDAFEGHFSRERLEDMGYKCEGC 360
            ..||||::||.|...|... |.|.|.|..|.|||:  |..:::||.|...:||.::  ||..: .
Mouse   623 TGIFGGHIRSVVYQQSSKE-SATLQLFFTLQLDIQSDKIRTVQDALESLVARESVQ--GYTTK-T 683

  Fly   361 KKKVSATKQFSLERAPITLCIQLKRF--SMIG--NKLTKQISFKSRIDLSKY----AARSQAAQA 417
            |::|..:::.:||:.|..|.:.||||  ...|  .||.|.|.:...:::|:.    ..:::..:.
Mouse   684 KQEVEVSRRVTLEKLPPVLVLHLKRFVYEKTGGCQKLVKNIDYPVDLEISRELLSPGIKNKNFKC 748

  Fly   418 QPLTYRLVSMVTHLGASQHCGHYTAIGSTDT-----GSFYNFDDSYVRPIAMHSV----CNTNAY 473
            | .||||.::|.|.|.|...||||    ||.     ..:...||..|:.|..:.|    .:..||
Mouse   749 Q-RTYRLFAVVYHHGNSATGGHYT----TDVFQIGLNGWLRIDDQTVKVINQYQVVKPPADRTAY 808

  Fly   474 IMFF-ELDL 481
            :::: .:||
Mouse   809 LLYYRRVDL 817

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scny	NP_729092.1	Peptidase_C19E	171..477	CDD:239126	104/402 (26%)
Usp10	XP_006530908.1	Peptidase_C19	540..813	CDD:239072	77/285 (27%)