DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment scny and usp-3

DIOPT Version :9

Sequence 1:	NP_729092.1	Gene:	scny / 38648	FlyBaseID:	FBgn0260936	Length:	1038	Species:	Drosophila melanogaster
Sequence 2:	NP_493434.3	Gene:	usp-3 / 190579	WormBaseID:	WBGene00013506	Length:	550	Species:	Caenorhabditis elegans

Alignment Length:	328	Identity:	102/328 - (31%)
Similarity:	159/328 - (48%)	Gaps:	38/328 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   173 GMINVGNTCYLNSTLQALLHIPALANWLVSEQAHLADC--NVAEPGSGCIICAMT---KTLLATQ 232
            ||.||||||::|:.||||..|.....:::| .:.|.|.  :..||.:|...|.:|   :.||.:|
Worm   230 GMRNVGNTCFMNAVLQALASISEFREYIMS-LSSLEDYIHDEKEPKNGGNYCYLTDEYRKLLISQ 293

  Fly   233 SNQSAVRP---------FLIYSKLKQICKHMVVGRQEDAHEFLRFLVEAMERAYLMRFRNYKELD 288
            |.:|...|         |:      .:|......||.|:|||:|:.::::.    ...|..::|.
Worm   294 SARSFREPTAPNEFREAFI------SVCPRFRGFRQHDSHEFMRYFMDSLH----TEMRKCRKLP 348

  Fly   289 QLVKET-TPLGQIFGGYLRSEVRCLSCNHVSITFQHFQDLLLDI---RKADS--LEDAFEGHFSR 347
            .:..:. ||:.:.|.|.|:|.|.|.:|.:.|.....|.||.|||   |.|..  |.|.....|..
Worm   349 GMPDDKHTPISKYFEGTLQSSVICQTCRNCSNKIDEFMDLSLDIPAQRNASKVRLSDCLSTFFKL 413

  Fly   348 ERLEDMGYK--CEGCKKKVSATKQFSLERAPITLCIQLKRFSMIGNKLTKQISF-KSRIDLSKYA 409
            |.|| .|.|  |..||.|.:.:||..:.:.|..||:.:|||...|.|....|.| ..::|::::.
Worm   414 EMLE-KGEKPECAKCKTKQTCSKQMFIRKLPQVLCLHMKRFRDNGGKNDAIIDFPMGQLDVTQFL 477

  Fly   410 ARSQAAQAQPLTYRLVSMVTHLGASQHCGHYTAIGSTDTGSFYNFDDSYVRPIAMHSVCNTNAYI 474
              :..:...|.||.|.|::.|:|.....|||.|.|..: |.::.|||:.|:.:....|....||:
Worm   478 --TDDSDEAPCTYSLQSIIVHIGYGCGSGHYIAFGKRN-GRWFQFDDTVVKGVDEAHVSKQKAYV 539

  Fly   475 MFF 477
            :.:
Worm   540 LLY 542

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
scny	NP_729092.1	Peptidase_C19E	171..477	CDD:239126	102/326 (31%)
		UCH	172..477	CDD:278850	102/326 (31%)
		Asp-B-Hydro_N	<617..>731	CDD:191249
usp-3	NP_493434.3	zf-UBP	53..111	CDD:366940
usp-3	NP_493434.3	UCH	229..542	CDD:366104	102/326 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	3	2.870