Protein Alignment scny and Usp17lc

DIOPT Version :9

• Sequence 1: NP_729092.1
• Gene: scny / 38648
• FlyBaseID: FBgn0260936
• Length: 1038
• Species: Drosophila melanogaster
• Sequence 2: NP_034219.3
• Gene: Usp17lc / 13532
• MGIID: 107698
• Length: 545
• Species: Mus musculus
• Alignment Length: 583
• Identity: 147/583 - (25%)
• Similarity: 250/583 - (42%)
• Gaps: 125/583 - (21%)

  Fly   168 WQV----GTGMINVGNTCYLNSTLQALLHIPALANWLVSEQAHLADCNVAEPGSGCIICAM---- 224
            |:.    |.|:.|.||:||||:.||.|.|.|.||::::|::.....|:    ..||.:|||
Mouse    43 WECPQGPGCGLQNTGNSCYLNAALQCLTHTPPLADYMLSQEYSQTCCS----PEGCKMCAMEAHV 103

  Fly   225 TKTLLATQSNQSAVRPFLIYSKLKQICKHMVVGRQEDAHEFLRFLVEAMERAYLMRFRNYKELDQ 289
            |::||.:.|. ..::|..|.:  ....||    :||||||||.|.:|.|..:.|   :.:::.:.
Mouse   104 TQSLLHSHSG-DVMKPSQILT--SAFHKH----QQEDAHEFLMFTLETMHESCL---QVHRQSEP 158

  Fly   290 LVKETTPLGQIFGGYLRSEVRCLSCNHVSITFQHFQDLLLDIRKADSLEDAFEGHFSRERLEDM- 353
            ..::::|:..||||..||:::||.|...|.|:..|.|:.|||..|.|:..|.   :..|:.|::
Mouse   159 TSEDSSPIHDIFGGLWRSQIKCLHCQGTSDTYDRFLDVPLDISSAQSVNQAL---WDTEKSEELR 220

  Fly   354 ---GYKCEGCKKKVSATKQFSLERAPITLCIQLKRFS-MIGNKLTKQISFKSRIDLSKYAARSQA 414
               .|.|..|::|:.|:|...:..||..|.:.||||| .:||||.:::|:...:||..|.::...
Mouse   221 GENAYYCGRCRQKMPASKTLHIHSAPKVLLLVLKRFSAFMGNKLDRKVSYPEFLDLKPYLSQPTG 285

  Fly   415 AQAQPLTYRLVSMVTHLGASQHCGHYTAIGSTDTGSFYNFDDSYVRPIAMHSVCNTNAYIMFF-- 477
            .   ||.|.|.:::.|.||:.|.|||.:......|::|..||:.|....:.||.|.|||::|:
Mouse   286 G---PLPYALYAVLVHEGATCHSGHYFSYVKARHGAWYKMDDTKVTSCDVTSVLNENAYVLFYVQ 347

  Fly   478 ELDLSQAASPAANRPNGVRLTNGHSTTPVPAATVSSPSPTRFIGPQLPAGGANGYTNGNAQKTAI 542
            :.||.|                                    :...:|.|..:...:...|....
Mouse   348 QTDLKQ------------------------------------VSIDMPEGRVHEVLDPEYQLKKS 376

  Fly   543 QFKQQNQQSPQNGLQLGTGKFQDTAKP------PLVGAHAKGEATSAPTANGNKSSSPSSNS--- 598
            :.|:..::||..         :|..:|      ......:.||.......|..|:.....|:
Mouse   377 RRKKHKKKSPCT---------EDAGEPCKNREKRATKETSLGEGKVLQEKNHKKAGQKHENTKLV 432

  Fly   599 --SSNHKSINQQQYLPISSDDEDIEDEMKPRPTTAQLPSMPNMTENHTEPKAKSPVKIQVKTPVK 661
              ..||:.:.|:..:          :|:.|:            .:||  .||...:: ..:..:.
Mouse   433 PQEQNHQKLGQKHRI----------NEILPQ------------EQNH--QKAGQSLR-NTEGELD 472

  Fly   662 TPLKSLVPY---------ESASEEEEAPLPNPRKRPSGEDSSESDQESGQTNGHSKTNGSHTN 715
            .|..::|.:         ..|.::|..|..|..:..:.:|...:.|...|........|.:.|
Mouse   473 LPADAIVIHLLRSTENWGRDAPDKENQPWHNADRLLTSQDPVNTGQLCRQEGRRRSKKGKNKN 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scny	NP_729092.1	Peptidase_C19E	171..477	CDD:239126	109/314 (35%)
		UCH	172..477	CDD:278850	108/313 (35%)
		Asp-B-Hydro_N	<617..>731	CDD:191249	17/108 (16%)
Usp17lc	NP_034219.3	Peptidase_C19E	50..346	CDD:239126	110/315 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	368..442		13/82 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	489..539		9/47 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	209	1.000	Domainoid score	I2834
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000177
OrthoInspector	1	1.000	-	-		otm44363
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24006
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.010