Protein Alignment scny and Usp17la

DIOPT Version :9

• Sequence 1: NP_729092.1
• Gene: scny / 38648
• FlyBaseID: FBgn0260936
• Length: 1038
• Species: Drosophila melanogaster
• Sequence 2: NP_031913.1
• Gene: Usp17la / 13531
• MGIID: 107699
• Length: 526
• Species: Mus musculus
• Alignment Length: 583
• Identity: 156/583 - (26%)
• Similarity: 243/583 - (41%)
• Gaps: 132/583 - (22%)

  Fly   155 ENIRIGWKQSERKWQ----VGTGMINVGNTCYLNSTLQALLHIPALANWLVSEQAHLADCNVAEP 215
            |.:.:..|.| ..|:    .|.|:.|.||:||||:.||.|.|.|.||::::| |.|...|...|
Mouse    31 EELTVNGKHS-LSWESPQGPGCGLQNTGNSCYLNAALQCLTHTPPLADYMLS-QEHSQTCCSPE- 92

  Fly   216 GSGCIICAMTKTLLATQSNQSAVRPFLIYSKLKQICK--HMVVG-----RQEDAHEFLRFLVEAM 273
              ||.:|||  ..|.|||        |::|....:.|  |::..     :||||||||.|.:|.|
Mouse    93 --GCKLCAM--EALVTQS--------LLHSHSGDVMKPSHILTSAFHKHQQEDAHEFLMFTLETM 145

  Fly   274 ERAYLMRFRNYKELDQLVKETTPLGQIFGGYLRSEVRCLSCNHVSITFQHFQDLLLDIRKADSLE 338
            ..:.|...|..|...:   :::|:..||||:.||:::||.|...|.|:..|.|:.|||..|.|::
Mouse   146 HESCLQVHRQSKPTSE---DSSPIHDIFGGWWRSQIKCLLCQGTSDTYDRFLDIPLDISSAQSVK 207

  Fly   339 DA-FEGHFSRERLEDMGYKCEGCKKKVSATKQFSLERAPITLCIQLKRFS-MIGNKLTKQISFKS 401
            .| ::...|.|...|..|.|..|::|:.|:|...:..||..|.:.|.||| ..||||.:::|:..
Mouse   208 QALWDTEKSEELCGDNAYYCGKCRQKMPASKTLHVHIAPKVLMVVLNRFSAFTGNKLDRKVSYPE 272

  Fly   402 RIDLSKYAARSQAAQAQPLTYRLVSMVTHLGASQHCGHYTAIGSTDTGSFYNFDDSYVRPIAMHS 466
            .:||..|.:.....   ||.|.|.:::.|.||:.|.|||........|.:|..||:.|....:.|
Mouse   273 FLDLKPYLSEPTGG---PLPYALYAVLVHDGATSHSGHYFCCVKAGHGKWYKMDDTKVTRCDVTS 334

  Fly   467 VCNTNAYIMFF--ELDLSQAASPAANRPNGVRLTNGHSTTPVPAATVSSPSPTRFIGPQLPAGGA 529
            |.|.|||::|:  :.:|.|                                    :...:|.|..
Mouse   335 VLNENAYVLFYVQQANLKQ------------------------------------VSIDMPEGRI 363

  Fly   530 NGYTNGNAQKTAIQFKQQNQQSP---------QN-------GLQLGTGKFQDTAKPPLVGAHAKG 578
            |...:...|....:.|:..::||         :|       ...||.||......      |.|
Mouse   364 NEVLDPEYQLKKSRRKKHKKKSPFTEDLGEPCENRDKRAIKETSLGKGKVLQEVN------HKK- 421

  Fly   579 EATSAPTANGNKSSSPSSNSSSNHKSINQQQYLPISSDDEDIEDEMKPRPTTAQLPSMPNMTEN- 642
                |...:||....|   ...||:...|      :..:.::|.::   |..|.:...|..|.|
Mouse   422 ----AGQKHGNTKLMP---QKQNHQKAGQ------NLRNTEVELDL---PADAIVIHQPRSTANW 470

  Fly   643 -------HTEPKAKSPVKIQVKTPVKTPLKSLVPYESASEEEEAPLPNPRKRPSGEDSSESDQ 698
                   ..:|...:...:..:.||.|       ::...:|      ..|:...|::.::..|
Mouse   471 GRDSPDKENQPLHNADRLLTSQGPVNT-------WQLCRQE------GRRRSKKGQNKNKQGQ 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scny	NP_729092.1	Peptidase_C19E	171..477	CDD:239126	114/314 (36%)
		UCH	172..477	CDD:278850	113/313 (36%)
		Asp-B-Hydro_N	<617..>731	CDD:191249	14/90 (16%)
Usp17la	NP_031913.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		Peptidase_C19E	50..346	CDD:239126	115/315 (37%)
		UCH	51..345	CDD:278850	113/313 (36%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	374..394		3/19 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	465..494		3/28 (11%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	209	1.000	Domainoid score	I2834
eggNOG	1	0.900	-	-		E1_KOG1865
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000177
OrthoInspector	1	1.000	-	-		otm44363
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24006
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.910