DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ppat-Dpck and CAB4

DIOPT Version :9

Sequence 1:	NP_647985.1	Gene:	Ppat-Dpck / 38647	FlyBaseID:	FBgn0035632	Length:	518	Species:	Drosophila melanogaster
Sequence 2:	NP_011793.3	Gene:	CAB4 / 853194	SGDID:	S000003509	Length:	305	Species:	Saccharomyces cerevisiae

Alignment Length:	186	Identity:	60/186 - (32%)
Similarity:	99/186 - (53%)	Gaps:	7/186 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   123 LDDSVISDLSAQQDDTQPPKVYPSVVLGGTFDRIHLGHKIFLTQAVLRTCKRLVVGVTTSAMTKG 187
            |.|:::.::...:|..:    :....||||||.||.||||.|:.:...|.:||:.|:|...:.:.
Yeast   125 LHDNIMEEIEGPKDANK----FHVTALGGTFDHIHDGHKILLSVSTFITSQRLICGITCDELLQN 185

  Fly   188 KTLPDLILPVEERIARLREFLVDIDDTLQYEIVPIDDPFGPTQVDPDLDMIVVSAETLRGGQKVN 252
            |...:||.|.:.|...:.:|:..:...|..|:||:.|..|||...|:::.:|||.||:.|.:.||
Yeast   186 KKYKELIEPYDTRCRHVHQFIKLLKPDLSVELVPLRDVCGPTGKVPEIECLVVSRETVSGAETVN 250

  Fly   253 EVRSAKQLRELEIFVIDIVESNVHDGIHETKVSSSNTRIDLLGTRWRRPEPRPQLP 308
            :.|..|.:..|.:.|::::.....||..| |:||:..|..|..:  ..|...||.|
Yeast   251 KTRIEKGMSPLAVHVVNVLGGREEDGWSE-KLSSTEIRRLLKSS--ASPTCTPQNP 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ppat-Dpck	NP_647985.1	PPAT_CoAS	147..290	CDD:173915	51/142 (36%)
		CoaE	311..510	CDD:223315
		DPCK	313..494	CDD:238980
CAB4	NP_011793.3	PPAT_CoAS	144..288	CDD:173915	51/144 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	97	1.000	Domainoid score	I1625
eggNOG	1	0.900	-	-		E1_COG1019
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2476
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005202
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101466
Panther	1	1.100	-	-	LDO	PTHR10695
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4246
SonicParanoid	1	1.000	-	-		X3717
TreeFam	0	0.000	Not matched by this tool.
	9	8.790