Protein Alignment CG10576 and ARX1

DIOPT Version :10

• Sequence 1: NP_647984.1
• Gene: CG10576 / 38645
• FlyBaseID: FBgn0035630
• Length: 391
• Species: Drosophila melanogaster
• Sequence 2: NP_010386.1
• Gene: ARX1 / 851678
• SGDID: S000002508
• Length: 593
• Species: Saccharomyces cerevisiae
• Alignment Length: 496
• Identity: 104/496 - (20%)
• Similarity: 192/496 - (38%)
• Gaps: 169/496 - (34%)

  Fly     9 EKTIAEDLVVTKYKLAGEIVNKTLKAVIGLCVVDA----------SVREICTQGDNQLTEETGKV 63
            :|.|.::.|:.||:.||:|....||.|..| :.|:          :|.|:|...|:.:.....:.
Yeast    16 DKNILQESVLNKYRTAGQIAQTALKYVTSL-INDSYHSKTTQRQLTVPELCLLTDSFILTRLEQY 79

  Fly    64 YKKEKDLKKGIAFPTCLSVNNCVCHFSPAKNDADY------------------TLKAGDVVKIDL 110
            ||.:.: ::|||.||.:.::.....:.|..:|...                  ||:.||:|||.|
Yeast    80 YKNKVN-ERGIAIPTTIDIDQISGGWCPEIDDTQNLLNWNKGKDSTFASSVTGTLRPGDLVKITL 143

  Fly   111 GAHIDGFIAVAAHTIVVGAAADQK--------ISGRQADVILAAYWAVQAALRLL---------- 157
            |.||||:.:..:||:|:....:.|        :.|.:||.:.||:.|::..:.||
Yeast   144 GVHIDGYTSEVSHTMVIYPVDETKPILQPTGPLLGGKADAVAAAHIAMETVVALLACALTPEKLP 208

  Fly   158 ------KSGANNYSLTDAVQQISESYKCKPIEGMLSHELKQFKIDGEKTIIQNPSEAQR------ 210
                  .||.....:...|..|:.||.|..:.|.....:::|.....:.|:     |:|
Yeast   209 ASLGGTSSGITGQLIRTIVDTIARSYNCGVVPGSRVRRIRRFLAGQNEGIV-----AEREYKGVV 268

  Fly   211 --KEHEKC---------------------------------TFETYEVYAIDVIVSTGEGVGRE- 239
              :.|::.                                 ..::.|||.||:.:::.|...::
Yeast   269 WTESHQEADLLSNTDAKDLTVVDRGQSTPFTNVSAIPSDDFVVQSGEVYLIDLKMASLEHCTKKG 333

  Fly   240 ---KDTKVSIYKKSE-----------------ENYMLKMKASRALLAEVKTKYG----------- 273
               .:|..|...||.                 :.::||:|.||.||.:: .|.|
Yeast   334 LVTLETVDSYTGKSHKAGELIARPGAYVRDFAQTHILKLKTSRQLLTKI-DKQGVYPFKLSHLSS 397

  Fly   274 NMPF------NIRSFEEETKA-RMGVVE------CVGHKMIEPFQVLYEKPSEIVAQFKHTVLLM 325
            |.||      .::|.:::.|: |:|:.|      ||.    .|.|:....|.:.:.:..:
Yeast   398 NFPFVHENEEELQSLKKDLKSFRLGMSEISNNYLCVE----SPIQIARWVPWDHILKATN----- 453

  Fly   326 PNGVNLVTGIPFEAENYVS---------EYSVAQEELKTLL 357
            |||     .:.::|.:.::         :..|:..:||:|:
Yeast   454 PNG-----NLSYDATSTLTLPGHELPLPKLGVSAIKLKSLM 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10576	NP_647984.1	APP_MetAP	3..361	CDD:469704	104/496 (21%)
ARX1	NP_010386.1	APP_MetAP	25..>285	CDD:469704	61/266 (23%)