DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10576 and Metap1

DIOPT Version :9

Sequence 1:	NP_001286949.1	Gene:	CG10576 / 38645	FlyBaseID:	FBgn0035630	Length:	391	Species:	Drosophila melanogaster
Sequence 2:	NP_780433.1	Gene:	Metap1 / 75624	MGIID:	1922874	Length:	386	Species:	Mus musculus

Alignment Length:	115	Identity:	27/115 - (23%)
Similarity:	49/115 - (42%)	Gaps:	11/115 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 FP--TCLSVNNCVCHFSPAKNDADYTLKAGDVVKIDLGAHIDGFIAVAAHTIVVGAAADQKISGR 138
            ||  .|.|||..:||..|.:.    .|:.||:|.:|:..:.:|:......|..||   |.....|
Mouse   189 FPKSCCTSVNEVICHGIPDRR----PLQEGDIVNVDITLYRNGYHGDLNETFFVG---DVDEGAR 246

  Fly   139 QADVILAAYWAVQAALRLLKSGANNYSLTDAVQQISESYKCKPIEGMLSH 188
            :  ::...|..:..|:..:|.|.....|.:.:|:.:::.....:.....|
Mouse   247 K--LVQTTYECLMQAIDAVKPGVRYRELGNIIQKHAQANGFSVVRSYCGH 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10576	NP_001286949.1	APP_MetAP	3..361	CDD:294199	27/115 (23%)
Metap1	NP_780433.1	Zinc finger-like, important for proper ribosome association. /evidence=ECO:0000255\|HAMAP-Rule:MF_03174	9..52
Metap1	NP_780433.1	APP_MetAP	14..382	CDD:320876	27/115 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900