DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10576 and ApepP

DIOPT Version :9

Sequence 1:	NP_001286949.1	Gene:	CG10576 / 38645	FlyBaseID:	FBgn0035630	Length:	391	Species:	Drosophila melanogaster
Sequence 2:	NP_001246053.1	Gene:	ApepP / 35029	FlyBaseID:	FBgn0026150	Length:	613	Species:	Drosophila melanogaster

Alignment Length:	170	Identity:	37/170 - (21%)
Similarity:	68/170 - (40%)	Gaps:	37/170 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 KTIAEDLVVTKYKLAGEIVNKTLKAVIGLCVVDASVREICTQGDNQLTEETG----KVYKKEKDL 70
            |.|..|:     ::|| .:|..::..:.||...|.:.:...:| .::.|.:|    :.::..||.
  Fly   311 KAIKNDV-----EIAG-FINSHIRDGVALCQYFAWLEDQVNKG-AEVDEMSGADKLESFRSTKDK 368

  Fly    71 KKGIAFPT--CLSVNNCVCHFSPAKNDADYTLKAGDVVKIDLGA-HIDGFIAVA----------- 121
            ..|::|.|  ....|..|.|:.| |.:.:..:...::...|.|| ::||...|.
  Fly   369 YMGLSFTTISASGPNGSVIHYHP-KKETNRKINDKEIYLCDSGAQYLDGTTDVTRTLHFGEPTEF 432

  Fly   122 ---AHTIVV-------GAAADQKISGRQADVIL-AAYWAV 150
               |:|.|:       ......|:.|:..|.:. .|.|.|
  Fly   433 QKEAYTRVLKGQLSFGSTVFPAKVKGQVLDTLARKALWDV 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10576	NP_001286949.1	APP_MetAP	3..361	CDD:294199	37/170 (22%)
ApepP	NP_001246053.1	Creatinase_N	9..154	CDD:307473
		Creatinase_N_2	158..318	CDD:318430	3/11 (27%)
		APP	321..545	CDD:238518	33/155 (21%)
		Peptidase_M24_C	551..613	CDD:318429
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456480
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930