Protein Alignment CG10576 and W08E12.7

DIOPT Version :9

• Sequence 1: NP_001286949.1
• Gene: CG10576 / 38645
• FlyBaseID: FBgn0035630
• Length: 391
• Species: Drosophila melanogaster
• Sequence 2: NP_500311.1
• Gene: W08E12.7 / 177097
• WormBaseID: WBGene00021088
• Length: 391
• Species: Caenorhabditis elegans
• Alignment Length: 363
• Identity: 173/363 - (47%)
• Similarity: 253/363 - (69%)
• Gaps: 2/363 - (0%)

  Fly    11 TIAEDLVVTKYKLAGEIVNKTLKAVIGLCVVDASVREICTQGDNQLTEETGKVYKKEKDLKKGIA 75
            |:|.|.|||||::|.||.|..||.|:......|...::|..||..:.|:|||:|||||:..||||
 Worm    22 TLANDAVVTKYQVAAEITNAVLKEVLANIKEGAIAGDLCDLGDKLILEKTGKLYKKEKNFTKGIA 86

  Fly    76 FPTCLSVNNCVCHFSPAKNDADYTLKAGDVVKIDLGAHIDGFIAVAAHTIVVGAAADQKISGRQA 140
            .|||:|::||:||::|.|::|...||.|.|||:|||.||||.||.||||:||||:.|.|::|:.|
 Worm    87 MPTCISIDNCICHYTPLKSEAPVVLKNGQVVKVDLGTHIDGLIATAAHTVVVGASKDNKVTGKLA 151

  Fly   141 DVILAAYWAVQAALRLLKSGANNYSLTDAVQQISESYKCKPIEGMLSHELKQFKIDGEKTIIQNP 205
            |::...:.|::.|:|.|:....|.::|..:.:.:..:...|||.||||:|::.:|||||.||||.
 Worm   152 DLLRGTHDALEIAIRSLRPDTENTTITKNIDKTAAEFGLTPIENMLSHQLERNEIDGEKKIIQNS 216

  Fly   206 SEAQRKEHEKCTFETYEVYAIDVIVSTGEGVGREKDTKVSIYKKSEE-NYMLKMKASRALLAEVK 269
            .|.|:.|.||...:.:|.||||::.|||:|..::.||:.::::|:|: :|.|||||||...::|.
 Worm   217 GEKQKGEIEKIKIDKHEAYAIDILFSTGKGQPKDMDTRTTVFRKNEQVSYQLKMKASRVFFSDVN 281

  Fly   270 TKYGNMPFNIRSFEEETKARMGVVECVGHKMIEPFQVLYEKPSEIVAQFKHTVLLMPNGVNLVTG 334
            ..:|.|||::||||||.||:||||||..:.::.|:.|||||..|:|||||.|||:||||:..:.|
 Worm   282 KVHGPMPFSLRSFEEEVKAKMGVVECEKYGLLVPYPVLYEKEGELVAQFKATVLVMPNGLLKIAG 346

  Fly   335 IPFEAENYVSEYSVAQEELKTLLAQPLGPVKGKGKGKK 372
            :||:::.|.|:.:|...||:.:|...|.| |.|.:.||
 Worm   347 LPFDSDVYQSDLTVKDPELQAVLKSALKP-KKKKEAKK 383

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10576	NP_001286949.1	APP_MetAP	3..361	CDD:294199	167/350 (48%)
W08E12.7	NP_500311.1	APP_MetAP	21..391	CDD:381919	173/363 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166233
Domainoid	1	1.000	193	1.000	Domainoid score	I1879
eggNOG	1	0.900	-	-		E1_COG0024
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4513
Inparanoid	1	1.050	354	1.000	Inparanoid score	I1313
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54050
OrthoDB	1	1.010	-	-		D375525at33208
OrthoFinder	1	1.000	-	-		FOG0002945
OrthoInspector	1	1.000	-	-		oto19999
orthoMCL	1	0.900	-	-		OOG6_101895
Panther	1	1.100	-	-	LDO	PTHR10804
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2037
SonicParanoid	1	1.000	-	-		X1946
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	15	14.840