Protein Alignment Usp47 and Usp30

DIOPT Version :10

• Sequence 1: NP_523937.2
• Gene: Usp47 / 38644
• FlyBaseID: FBgn0016756
• Length: 1556
• Species: Drosophila melanogaster
• Sequence 2: NP_572274.1
• Gene: Usp30 / 31519
• FlyBaseID: FBgn0029819
• Length: 558
• Species: Drosophila melanogaster
• Alignment Length: 630
• Identity: 130/630 - (20%)
• Similarity: 221/630 - (35%)
• Gaps: 181/630 - (28%)

  Fly   203 CPELSTEINSKNTSSESPVAKKTAKVTSKPTLELLS---------PIKPSSPIKELDC----EPV 254
            ||:....:...|.:|..   :|:...:...|||:::         |..|.:.::.|:.    .|.
  Fly    60 CPQFIAWLQLYNNASPD---RKSLITSMLNTLEVVNGTHATLRGDPYSPGAVLRALNALGWVIPQ 121

  Fly   255 DTLSKQQL-------SEQLQLYPQGRNLISPVDDAPSDLFISDAEQLSDDDLALGASASPTMLGP 312
            :.....:|       .|:..:.||....:|  |..|:|         :||:.:|..:|:|.
  Fly   122 EEHDAHELFHVLLTCLEEEAIRPQPLGCLS--DALPTD---------NDDNSSLAGTATPV---- 171

  Fly   313 GYDYGAPTGDSDVEGVTGVTDPSTIGTDDGTYPA---LSNFYRRKYGGDELRAWQRVNTTGADFV 374
                |.....|.:  ..|:.....|| |....|:   |::|...:|  ||..:.||:..:.|...
  Fly   172 ----GGFRSFSSM--AAGLGASQRIG-DQPNRPSSAMLTDFLNMEY--DESTSLQRLVRSEAHTP 227

  Fly   375 SSATTETEAEARQASLGPRGYVGLVNQAMTCYLNSLLQAL-----FMTPEFRNALYRWEFDNDNE 434
            .|..:..|.:... .||                :.||.|:     |..|...|
  Fly   228 DSPASVCERDGND-RLG----------------SVLLDAVSPGTPFGFPLVSN------------ 263

  Fly   435 AKNIPYQLQKLFLNLQTSPKAAVETTDLTRSFGWDSTEAWQQHD------IQELCRVMFDALEHK 493
                |..|....|..:.|.:..:             .::.||.|      :...||    :||..
  Fly   264 ----PDSLATPMLGGERSSRPRL-------------PQSQQQQDEGLNRRVSSSCR----SLERL 307

  Fly   494 FKNTKQANLISNL--------YEGKMNDYVKCLECNTEK-TREDTFLDIPLPVRPFGSSSAYGSI 549
            .:...:.::.||:        ::|.|...:.|..|.::. .|.|.|..|.|.:.|...:..  |:
  Fly   308 HRGPGRVSIWSNMMPSQVAHPFQGAMGAQIVCNGCGSKSAVRYDKFDSITLNLPPQRRTGL--SL 370

  Fly   550 EEALRAFVQPETLDGNNQYLCEKCKKKCDAHKGLHFKSFPYILTLHLKRFDFDYQTMHRIKLNDR 614
            ...|..::..|.|   :...|:.|.:.....|.:.|...|..|.:|:.|..: ..|....|..|.
  Fly   371 GHLLSEYITSEDL---SDVKCDSCNETTTHTKSVTFAKLPACLCIHVARTVW-LPTGQVCKRKDY 431

  Fly   615 VTFPQTLNLNTFINRSGNSGEQNSQLNGTVDDCSTADSGSAMEDDNLSSGVVTTASSSQHENDLN 679
            |.||::|::..:   |......|||. ||       ..||.|          :..|||...|  |
  Fly   432 VHFPESLSMAPY---SFVQPHLNSQA-GT-------PWGSTM----------SLYSSSLPMN--N 473

  Fly   680 DEDEGIDMSSSTSKSAKQGSGPYLYELFAIMIHSGSASGGHYYAYIKDFDNN--EWFCFNDQNVT 742
            ....|....:...|:        ||.|.|:::|||.|:.||:..|.:....|  .|:..:|..|.
  Fly   474 GVGGGEGFGTMFPKN--------LYRLLAVVVHSGEANSGHFVTYRRGSLRNAHRWYYTSDTIVR 530

  Fly   743 SITQEDIQRSFGGPNGSYYSSAYTSSTNAYMLMY-----RQVDAK 782
            .::.:::                 .|..||:|.|     ||::.:
  Fly   531 EVSIDEV-----------------LSVPAYLLFYDRGQQRQLNLR 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp47	NP_523937.2	DUF4045	<122..249	CDD:433066	10/54 (19%)
		peptidase_C19C	394..780	CDD:239124	86/412 (21%)
		USP47_C	1300..1534	CDD:466158
Usp30	NP_572274.1	Peptidase_C19	39..>139	CDD:470612	13/81 (16%)
		Peptidase_C19F	<323..548	CDD:239127	64/278 (23%)