Protein Alignment Usp47 and Usp25

DIOPT Version :9

• Sequence 1: NP_523937.2
• Gene: Usp47 / 38644
• FlyBaseID: FBgn0016756
• Length: 1556
• Species: Drosophila melanogaster
• Sequence 2: XP_038944372.1
• Gene: Usp25 / 304150
• RGDID: 1309003
• Length: 1125
• Species: Rattus norvegicus
• Alignment Length: 1254
• Identity: 254/1254 - (20%)
• Similarity: 394/1254 - (31%)
• Gaps: 437/1254 - (34%)

  Fly   312 PGYDYGAPTG---DSDVEGVTGVTDPSTIGTDDGTYPALSNFYRRKYG-GDELRAWQRVNTTGAD 372
            ||.|.....|   |::|..:|| .|...:........|.||...|:.| .||.:|..||......
  Rat    76 PGSDRYISVGSQADANVIDLTG-DDKDDLQRAIALSLAESNRTFRETGITDEEQAISRVLEASIA 139

  Fly   373 FVSSATTETEAEARQASLGP-------RGYVGLVNQAMTCYLNSLLQALFMTPEFRNALYRWEFD 430
            ...:....|..|..:.|..|       :..|||.|...||:.::::|:||...|||..:..::..
  Rat   140 ENKACLKRTPIEVWRDSRNPYDRKRQDKAPVGLKNVGNTCWFSAVIQSLFNLLEFRRLVLNYKPP 204

  Fly   431 --------NDNEAKNIPY--QLQKLFLNL------QTSPKAAVETTDLTRSFGWDSTEAWQQHDI 479
                    |..|.:|:|:  :|:.||..|      ...|..|||.  |..:|..:.:   ||.|:
  Rat   205 SNAQDLPRNQKEHRNLPFMRELRYLFALLVGTKRKYVDPSRAVEI--LKDAFKSNDS---QQQDV 264

  Fly   480 QELCRVMFDALEHKFK--------NTKQANLISNLY----------EGKMNDYVKCLECNTEKTR 526
            .|....:.|.||..|:        ..|..|.:..|:          |||..:       |||
  Rat   265 SEFTHKLLDWLEDAFQMKAEEETDEEKPKNPMVELFYGRFLAMGVLEGKKFE-------NTE--- 319

  Fly   527 EDTFLDIPLPVRPFGSSSAYGSIEEALRAFV---QPETLDGNNQYLCEKCKKKCDAHKGLHFKSF 588
              .|...||.|      :.:..:.|.|.|.:   :.|:|..:|.      .|....|   .|...
  Rat   320 --MFGQYPLQV------NGFKDLHECLEAAMIEGEIESLHSDNS------GKSGQEH---WFTEL 367

  Fly   589 PYILTLHLKRFDFDYQTMHRIKLNDRVTFPQTLNLNTFINR------------------------ 629
            |.:||..|.||:|:.......|:::::.|||.|.|:.:::|
  Rat   368 PPVLTFELSRFEFNQALGRPEKIHNKLEFPQVLYLDRYMHRNREITRIKREEIKRLKDYLTVLQQ 432

  Fly   630 ------SGNSGEQNSQL-----------------NGTVD--DCSTADSGSA-------------- 655
                  |..||.:...|                 ...||  |.:::.|||.
  Rat   433 RLERYLSYGSGPKRFPLVDVLQYALEFASSKPVCTSPVDDIDATSSTSGSTSSQSLPSTTEQQGT 497

  Fly   656 ----MEDDNLSSGVVTTASSSQH----------------------------------------EN 676
                :...:.:||...:..|..|                                        ||
  Rat   498 PASDLPSSSPASGAALSLRSVIHKPFTQSRIPPDLPMHPAPRHITEEELSVLESCLHRWRTEIEN 562

  Fly   677 DLNDEDEGIDMSSST------SKSAKQGSGPYLYELFAIMIHSGSASGGHYYAYIKDFDNNEWFC 735
            |..|..|.|.....|      .||..|    ..|.|.|:::|.|.|:.|||:|||.|...:.|..
  Rat   563 DTRDLQESISRIHRTIELMYSDKSMIQ----VPYRLHAVLVHEGQANAGHYWAYIFDHRESRWMK 623

  Fly   736 FNDQNVTSITQEDIQR-SFGGPNGSYYSSAYTSSTNAYMLMYRQVDAKRNELVAKVADFPEH--- 796
            :||..||..:.|::.| ||||     |.:|     :||.|||  ::.|...|:.:  :|.:.
  Rat   624 YNDIAVTKSSWEELVRDSFGG-----YRNA-----SAYCLMY--INDKAQFLIQE--EFNKETGQ 674

  Fly   797 ----IKTLLPKLHSEEETRVSRLGRHITVTDLALPDLYKPRVYFYNPSLKKMKITRVYVSQSFNI 857
                ::||.|.|....|....|..:.:...|..|.          ..:|::.
  Rat   675 ALVGMETLPPDLRDFVEEDNQRFEKELEDWDTQLA----------QRALQEK------------- 716

  Fly   858 NLVLMSAYEMLNVEQFAPLSRCRLVAYNSSMDTIIQSLESCTDPALTELRAAQNYSLDFLLEYRA 922
               |::|.::...|..||                                .||....|:|.:
  Rat   717 ---LLAAQKLREAESSAP--------------------------------TAQAGGPDYLEQ--- 743

  Fly   923 EDQEFEVYPPNGITWYVFKVDLSTMAMDGPFLVYSAAREREASDVLRRSIALRLHISEQQFLLAT 987
                     |:       :.|||                :...:...|.||...|..|.:
  Rat   744 ---------PS-------RSDLS----------------KHWKEETLRVIAKASHDHEDK----- 771

  Fly   988 VRATVPKAFVSYDPHPTPEALQHLQNMANTQFKSITYFYLNVPNTDAATLEMLGVPTVESVECAS 1052
                .|:..:...|..|.......|.....|...|..|                  .:||.|...
  Rat   772 ----GPETVLQSKPENTTSQPPSKQQAVEVQIPHIGKF------------------MIESKEGGY 814

  Fly  1053 GGDVVDAAMMNGVAPGHMSSSNDYD------------WRRYKRDLVEPMSQPSP----------- 1094
            ..:::....|.|:......|.:.||            ...|.| ||:...:.:|
  Rat   815 DDEIMMTPSMQGIIMAIGKSRSVYDRCGPEAGFFKAIKLEYSR-LVKLAQEDTPPETDYRLHHVL 878

  Fly  1095 -----SHGHESNSEDSSLSD-GDRTLVETDNMAHRGGGDSQVSSTSHSPQ---LSSPEDEAASHD 1150
                 :...:...|.:.|.. |||.| ..|...|.....:|.......|:   |...|:..|.:.
  Rat   879 VYFIQNQAPKKIIEKTLLEQFGDRNL-SFDERCHNIMKVAQAKLEMIKPEEVNLEEYEEWHADYK 942

  Fly  1151 AMMRVHAY-CNGNGSYAAADVVDPLLLPTSTNHFFYATKVECVDVVGTGSSSGHQSDEEAQLRKP 1214
            .......| ..|..::.....:|.||       |.........:::..|...||..|
  Rat   943 KFRETTMYLIIGLENFQRESYIDSLL-------FLICAYQNNKELLSKGPYRGHDGD-------- 992

  Fly  1215 TRAYKLLVGTHMRMGAFKKHIEQLIQVPAAHFKLQRKHDNNLSNN---QNNSLVHLI-------- 1268
                  |: :|.|.....|..||..::      .:...|..:||.   .|..:|..:
  Rat   993 ------LI-SHYRRECLLKLNEQAAEL------FESGEDREVSNGLIIMNEFIVPFLPLLLVDET 1044

  Fly  1269 -EGETLTVE---------LGKTLEPDEFKAKIHFL-RLADID------NETSKLPCVCEWVYNAN 1316
             |.:.|.||         ||:.:||:..:....|| :|.|..      :|..|||.     |:|:
  Rat  1045 EERDILAVEDMRNRWCSYLGQDMEPNLQEKLTDFLPKLLDCSTEIKGFHEPPKLPS-----YSAH 1104

  Fly  1317 TTAEQAKKELVAKLHRIDA 1335
            ...|:..: ::..|.|..|
  Rat  1105 ELCERFAR-IMLSLSRTPA 1122

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp47	NP_523937.2	TEBP_beta	<119..234	CDD:254188
		Rib_recp_KP_reg	122..265	CDD:282899
		peptidase_C19C	394..780	CDD:239124	125/536 (23%)
		UCH	395..776	CDD:278850	123/531 (23%)
Usp25	XP_038944372.1	UBA_UBP25	15..60	CDD:270539
		UBP14	<170..637	CDD:227532	113/502 (23%)
		Peptidase_C19I	171..656	CDD:239130	124/532 (23%)
		USP25_C	838..1118	CDD:380451	60/315 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5077
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810