Protein Alignment Usp47 and ubp15

DIOPT Version :9

• Sequence 1: NP_523937.2
• Gene: Usp47 / 38644
• FlyBaseID: FBgn0016756
• Length: 1556
• Species: Drosophila melanogaster
• Sequence 2: NP_595341.1
• Gene: ubp15 / 2541131
• PomBaseID: SPBC713.02c
• Length: 1129
• Species: Schizosaccharomyces pombe
• Alignment Length: 1203
• Identity: 288/1203 - (23%)
• Similarity: 472/1203 - (39%)
• Gaps: 346/1203 - (28%)

  Fly   290 DAEQLSDDD--------LALGASASPTMLGPGYDYGAPTGDSDVEGVTGVTDPSTIG--TDDGTY 344
            |.|.::|:.        |:|.....||::.....:.....:....|.|...|...|.  |.:...
pombe   126 DPEIVNDETYSCCAQFALSLSNVQDPTVMQINTSHHRFRSEVKDWGFTRFVDLRKIAVPTPEFPV 190

  Fly   345 PALSNFYRRKYGGDEL------RAWQRVNTTGADFVSSATTETEAEARQASLGPRGYVGLVNQAM 403
            |.|.|        ||:      |..|  :.||..:.|.....::.|.        |||||.||..
pombe   191 PFLEN--------DEICISVTVRVLQ--DPTGVLWHSFVNYNSKKET--------GYVGLKNQGA 237

  Fly   404 TCYLNSLLQALFMTPEFRNALYRWEFDNDNEAKNIPYQLQKLFLNLQTSPKAAVETTDLTRSFGW 468
            |||:|||||:||.|..||..:|:...|||:...::.|.||::|.||: ..:..|.||:|||||||
pombe   238 TCYMNSLLQSLFFTNIFRKTVYKIPTDNDDSRDSVAYALQRVFYNLE-KQREPVSTTELTRSFGW 301

  Fly   469 DSTEAWQQHDIQELCRVMFDALEHKFKNTKQANLISNLYEGKMNDYVKCLECNTEKTREDTFLDI 533
            :|.:::.||||||..||:.|.||.|.|.|:..|.:::::.|||..||||::.|.|.:|.:.|.||
pombe   302 NSFDSFMQHDIQEFNRVLQDNLEKKMKGTEVENALNDIFVGKMKSYVKCIDVNYESSRVEDFWDI 366

  Fly   534 PLPVRPFGSSSAYGSIEEALRAFVQPETLDGNNQYLCEKCKKKCDAHKGLHFKSFPYILTLHLKR 598
            .|.|:      ...::|::.|..:|.|||.|:|:|..|....: |||||:.|:|.|.:|.|.|||
pombe   367 QLNVK------GMDTLEDSFRDAIQVETLTGDNKYYAEGHGLQ-DAHKGIIFESLPNVLQLQLKR 424

  Fly   599 FDFDYQTMHRIKLNDRVTFPQTLNLNTFINRSGNSGEQNSQLNGTVDDCSTADSGSAMEDDNLSS 663
            ||:|......:|:|||..||..::|..:::.:.:..|.
pombe   425 FDYDMLRDMMVKINDRHEFPLEIDLEPYLSETADKSES--------------------------- 462

  Fly   664 GVVTTASSSQHENDLNDEDEGIDMSSSTSKSAKQGSGPYLYELFAIMIHSGSASGGHYYAYIKDF 728
                                                  ::|.|..:::|.|...||||||.||..
pombe   463 --------------------------------------HVYVLHGVLVHGGDLHGGHYYALIKPE 489

  Fly   729 DNNEWFCFNDQNVTSIT-QEDIQRSFGG-PNG---SYYSSAYTSSTNAYMLMYRQVDAKRNELVA 788
            .::.||.|:|..||..| :|.::.::|| |.|   .|..:.:....|||||:|.: .::.:.:::
pombe   490 KDSNWFKFDDDRVTRATIKEVLEDNYGGEPAGRAKGYNGNPFKRFMNAYMLVYFR-KSRLDHILS 553

  Fly   789 KVA--DFPEHIKTLLPKLHSEEETRVSRLGRHITVTDLALPDLYKPRVYFYNPSLKKMKITRVYV 851
            .|.  |.|.|::..|     :||.|         |.:..|.:..:.::|         :..||..
pombe   554 PVTAEDVPFHVRNTL-----DEEHR---------VVERKLLEREEQQIY---------RRVRVLT 595

  Fly   852 SQSFNINLVLMSAYEMLNVEQFAPLSRCRLVAYNSSMDTIIQSLESCTDPALTELRAAQNYSLDF 916
            :..|       ..|...::..|:                     .|..||.|...:..:|.::..
pombe   596 TDGF-------KKYHGFDMTDFS---------------------ASDDDPVLITTKIKRNANIWD 632

  Fly   917 LLEYRA----EDQEFEVYPPNGI-TWYVFKVDLSTMAMDGPFLVYSAAREREASDVLRRSIALRL 976
            |.::.|    .|       .:|| .|.:......|:.:|.|....:...::.....:|:.:.:|:
pombe   633 LQKHLAGLLNRD-------TSGIRIWLMTNRQNRTVRVDLPLDKKTILVDQICDMHIRKDMDMRV 690

  Fly   977 HI---SEQQFLLATVRATVPKAFVSYDPHPTPEALQHLQNMANTQFKSITYFYLNVPNTDAATLE 1038
            ::   ||...|||...||....|                         .||.:|.:  .|..|.:
pombe   691 YVEFLSEHNQLLADFGATDDNDF-------------------------DTYIFLKI--FDYETQQ 728

  Fly  1039 MLGVPTVESVECASGGDVVDAAMMNGVAPGHMSSSNDYDWRRYKR------DLVEPMSQPSPSHG 1097
            :.|:..:.    .|....:.:  ::.....|:..|:|.....|:.      |:::|
pombe   729 ISGLADLH----VSKNSPISS--LSEWIREHLKWSSDVPITYYEEIKTGMVDVLDP--------- 778

  Fly  1098 HESNSEDSSLSDGDRTLVETDNMAHRGGGDSQVSSTSHSPQLSSPEDEAASHDAMMRVHAYCNGN 1162
             .::.|.|.:..||....| ..:.|    ||. |.|||..:.:....:..:|..::......:.:
pombe   779 -NASFEKSEIQVGDIICFE-KKLVH----DSS-SDTSHPYKSALDLYDFMAHRVVITFEPRYSDD 836

  Fly  1163 GSYAAADVVDPLLLPTSTNHFFYATKVECVDVVGTGSSSGHQSDEEAQLRKPTRAYKLLVGTHMR 1227
            .:....|    |:|.|.||:...|..|                           |.||.|..:
pombe   837 TNNGVFD----LVLTTHTNYTDMARAV---------------------------ANKLNVDPN-- 868

  Fly  1228 MGAFKKHIEQLIQVPAAH---------------FKLQRKHDNNLSNNQNNSLVHLIEGETLTVEL 1277
                      .:|...||               |.||....:..|:|||..:.:    |.|.:.|
pombe   869 ----------YLQFTMAHLPSRTPRSVIRNPSKFTLQNAIPSTYSHNQNVVMFY----EVLDITL 919

  Fly  1278 GKTLEPDEFKAKIHFLRLADIDNETSKLPCVCEWVYNANTTAEQAKKELVAK--LHRIDAKYATL 1340
            .: ||..:. .::|||. ..|.:||.     .|:..:...|.|...:::..|  |:..||....|
pombe   920 SE-LERKQL-IRVHFLS-NGISHETQ-----MEFYVDKEGTVEDILRQVTQKVPLNAEDASRLRL 976

  Fly  1341 -SVQNCRIWLKGGRIP---IKILSDDETLYCDMRSSIAAEFIVQECEEEVDPQPKDDSLTLFVRR 1401
             .|.|.|| || ..:|   |..|::..|.|.::..           :||......||::::.|:.
pombe   977 YEVYNHRI-LK-SHLPTDGIYDLNEFSTAYVEVTP-----------KEEQMQLKTDDAVSIVVQH 1028

  Fly  1402 WCPAKLEFGKFQEITLDQDSEIRLSLSQISDIP 1434
            :         |::            ||::.|||
pombe  1029 F---------FKD------------LSRLHDIP 1040

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp47	NP_523937.2	TEBP_beta	<119..234	CDD:254188
		Rib_recp_KP_reg	122..265	CDD:282899
		peptidase_C19C	394..780	CDD:239124	136/390 (35%)
		UCH	395..776	CDD:278850	134/385 (35%)
ubp15	NP_595341.1	COG5077	13..1129	CDD:227409	288/1203 (24%)
		MATH_Ubp21p	52..205	CDD:239744	17/86 (20%)
		peptidase_C19C	228..547	CDD:239124	136/392 (35%)
		USP7_ICP0_bdg	648..888	CDD:289221	56/331 (17%)
		USP7_C2	909..1111	CDD:291217	41/178 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5077
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810