Protein Alignment Usp47 and usp-48

DIOPT Version :9

• Sequence 1: NP_523937.2
• Gene: Usp47 / 38644
• FlyBaseID: FBgn0016756
• Length: 1556
• Species: Drosophila melanogaster
• Sequence 2: NP_001361851.1
• Gene: usp-48 / 172782
• WormBaseID: WBGene00009267
• Length: 1264
• Species: Caenorhabditis elegans
• Alignment Length: 1152
• Identity: 228/1152 - (19%)
• Similarity: 376/1152 - (32%)
• Gaps: 412/1152 - (35%)

  Fly   380 ETEAEA----RQASLGPRGYVGLVNQAMTCYLNSLLQALFMTPEFRNALYRWEFDNDN----EAK 436
            ||:.||    ::..|..:. .||:|....||:||.||..|..||||..:|.:. .::|    ||.
 Worm    89 ETKEEAKKDQKRRDLNDQP-AGLINGGNFCYVNSFLQVWFNVPEFRQLIYDFR-PSENFVPPEAP 151

  Fly   437 NIPYQ-----LQKLFLNLQTSPKAAVETTDLTRSFGWDSTEAWQQHDIQELCRVMFDALEH---K 493
            .:..|     ||.:|..|||:|   ...||.|.:.|.......:|.|.||.....|:|||.   .
 Worm   152 RMNVQATMLALQDIFYTLQTTP---FNETDKTSNLGKLLRLNSEQQDSQEFGLKFFNALERCLPD 213

  Fly   494 FKNTKQA-NLISNLYEGKMNDYVKCLECNTEKTREDTFLDIPLPVRPFGSSSAYGSIEEALRAFV 557
            ..|.|:. ..:.:|:.|:....:.| :|.....||:|.:.:.|.:      ..|.::.:||.|:.
 Worm   214 HPNGKETLKRLKDLFTGETCTRIVC-KCGQRSEREETAISLTLNI------EGYCTLLDALDAYF 271

  Fly   558 QPETLDGNNQYLCEKCKKKCDAHKGLHFKSFPYILTLHLKRFDFDYQTMHRIKLNDRVTFPQTLN 622
            ..|.||   .:.|.||.|..|..|...:...|.::.:.|.|  :.|.:..|.||...:.:|:.:.
 Worm   272 GEEHLD---DFKCSKCNKTGDVSKQSDYVKLPPVIVIQLNR--YKYTSKGRQKLKTPMAYPREIP 331

  Fly   623 LNTFINRSGNSGEQNSQLNGTVDDCSTADSGSAMEDDNLSSGVVTTASSSQHENDLNDEDEGIDM 687
            ...| .|:.||....::
 Worm   332 AKAF-QRTNNSIPPPAE------------------------------------------------ 347

  Fly   688 SSSTSKSAKQGSGPYLYELFAIMIHSG-SASGGHYYAYIKDFDNNEWFCFNDQNVTSI------- 744
                           :|:|||:.||.| :|..||||..||...|.:|:.:||:.:.:|
 Worm   348 ---------------MYDLFAVTIHEGNNAECGHYYDLIKSPLNQKWYRYNDEAIEAIPKPPGTE 397

  Fly   745 --TQEDIQRSFGGPNGSYYSSAYTSSTNAYMLMYRQVDAKRNELVAKVADFPEHIKTLLPKLHSE 807
              |....::|.......|    .|.....|.|:||:.||.:        ..|.      |||..|
 Worm   398 KPTTAKTEKSRKKDKEKY----PTDQKACYGLLYRRRDAFK--------PLPH------PKLPPE 444

  Fly   808 E-----ETRVSRLGRHITVTDLALPDLYKPRVYFYNPSLKKMKITRVYVSQSFNINLVLMSAYEM 867
            |     :|.:..|...:|...:   :..:.|:|.....:.|:||       |:.........|:.
 Worm   445 ELIIDSKTEIEELFEGLTKKKI---EKSEKRLYDLERRINKVKI-------SYGKLETHSDKYKE 499

  Fly   868 LNVEQFAPLSRCRLVAYNSSMDTIIQSLESCT-DPALTELRAAQNYSLDFLLEYRAEDQEFEVYP 931
            .|...|.|.:..:        |.:.|..|... :....:..|::|       |.:.:::|.|
 Worm   500 ANEVVFLPTTLLQ--------DVLAQEYEVAKGEKKKKKKEASEN-------EEKKKNEEDE--- 546

  Fly   932 PNGITWYVFKVDLSTMAMDGPFLVYSAAREREASDVLRRSIALRLHISEQQFLLATVRATVPKAF 996
                            |:........|.:..:||             ||.....|...|...:..
 Worm   547 ----------------ALSAAIAASEADQRDKAS-------------SEPSTSAAATEAGDDEEL 582

  Fly   997 VSYDPHPTPEALQHLQNMANTQFKSITYFYLNVPNTDAATLE----MLGVPTVESVECASGGDVV 1057
            .:....|.||                     |..:|..|.:|    |...||.:.       |::
 Worm   583 RAESETPNPE---------------------NAESTQVAIMETDEIMDTTPTKDI-------DIL 619

  Fly  1058 DAAMMNGVAPGHMSSSNDYDWRRYKRDLVEPMSQPSPSHGHESNSEDSSLSDGDRTLV---ETDN 1119
            ..||.:...|                    .:..|.|.....:..:     :|:...|   .|..
 Worm   620 AKAMEDNALP--------------------TVEVPQPELKKRTRQQ-----NGEVKYVYSQRTPR 659

  Fly  1120 MAHRGGGDSQVSSTSHSPQLSSPEDEAASHDAMMRVHAY--CNGNGSYAAADVVDPLLLPTSTNH 1182
            .:|.|     .:.|:.|||........|   |::..|..  | |:|..:    :||:|
 Worm   660 KSHNG-----TNGTNSSPQKQPVSSRVA---ALLSSHEIPTC-GHGKMS----IDPIL------- 704

  Fly  1183 FFYATKVECVDVVGTGSSSGHQSDEEAQLRKPT----RAYKLLVGTHMRMGAFKKHIEQLIQVPA 1243
                                 ..|.:|..|.|.    |.|
 Worm   705 ---------------------YGDVKAVSRAPAIALLREY------------------------- 723

  Fly  1244 AHFKLQRKHDNN---LSNNQNNSLVHLIEGETLTVE----------LGKTLEPDEFKAKIHFLRL 1295
             .|:::..:||.   ...|:....|.:...|.:.:|          ....||.||...:    |:
 Worm   724 -DFRVKIVYDNGENVFPENEKERDVFIFTAEDICMECVREMREEGNFNNQLEDDEKLVR----RI 783

  Fly  1296 ADIDNETSKLPCVCE----WVY-------NANTTAEQAKKELVAKLH----------------RI 1333
            ...:.:...:.|..|    ::|       |...:|..|::..:|:.|                :.
 Worm   784 LKEEKQRCSVKCPSERPDGYLYVAKFALSNFKKSAMSARENRLAQSHNKQGTLHFDSHPMFQQKS 848

  Fly  1334 DAKYATLSVQNCR-------------------IWLKGGRIPIKILSDDETLYCDMRSSIAAEFIV 1379
            ::.|.|||::..|                   |..|  .:|.:|::|:|.:..:|.|.|..:.:
 Worm   849 NSGYLTLSLKRTRGKPRKSLSEIPEKMQKLDEIGSK--ELPDEIIADEEEISENMGSDIPTKPV- 910

  Fly  1380 QECEEEVDPQPKDDSLTLFVRRWCPAKLEFGKFQEITLDQDSEIRLS 1426
                |.::|    |:|..|      .|:||          :||:|.|
 Worm   911 ----ESINP----DALVPF------EKIEF----------NSELRCS 933

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp47	NP_523937.2	TEBP_beta	<119..234	CDD:254188
		Rib_recp_KP_reg	122..265	CDD:282899
		peptidase_C19C	394..780	CDD:239124	100/408 (25%)
		UCH	395..776	CDD:278850	98/403 (24%)
usp-48	NP_001361851.1	UCH	108..394	CDD:395355	92/365 (25%)
		Ubiquitin_like_fold	1161..1264	CDD:421700

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5077
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D387934at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820