Protein Alignment Usp47 and usp28

DIOPT Version :9

• Sequence 1: NP_523937.2
• Gene: Usp47 / 38644
• FlyBaseID: FBgn0016756
• Length: 1556
• Species: Drosophila melanogaster
• Sequence 2: XP_002937867.3
• Gene: usp28 / 100492386
• XenbaseID: XB-GENE-990711
• Length: 1104
• Species: Xenopus tropicalis
• Alignment Length: 1090
• Identity: 211/1090 - (19%)
• Similarity: 378/1090 - (34%)
• Gaps: 345/1090 - (31%)

  Fly   396 VGLVNQAMTCYLNSLLQALFMTPEFRNALYRWEF--------DNDNEAKNIPY--QLQKLFLNLQ 450
            |||.|...||:.::::|:||..||||..::.:..        .:.:|.:|:.:  :||.||..:.
 Frog   138 VGLKNIGNTCWFSAVIQSLFHLPEFRRLVHSYSITQSMLEKCQSRDEKRNLAFMQELQCLFTLMV 202

  Fly   451 TS------PKAAVETTDLTRSFGWDSTEAWQQHDIQELCRVMFDALEHKFKNT--------KQAN 501
            .|      |..|:|.  |..:|   .:|..||.|:.|....:.|.||..|:.|        |..|
 Frog   203 GSNRKFVDPSPALEL--LKDAF---LSEEAQQQDVSEFTHKLLDWLEDAFQLTVNGEDPRDKSEN 262

  Fly   502 LISNLYEGK-MNDYVKCLECNTEKTREDTFLDIPLPVRPFGSSSAYGSIEEALR-AFVQPETLDG 564
            .:..|:.|. :|:  ..||.|...:..:||...||.|      :.:.::.|.|. |.|:.|.
 Frog   263 PMVQLFYGTFLNE--GFLEANKAFSNIETFGQYPLQV------NGFSNLNECLEAAMVEGEI--- 316

  Fly   565 NNQYLCEKCKKKCDAHKGLHFKSFPYILTLHLKRFDFDYQTMHRIKLNDRVTFPQTLNLNTFI-- 627
            .|....:..:.:.:.    .|...|.:||..|.||:|:.......|:::::.||:.:.::.|:
 Frog   317 ENMQTAQSARYRQER----WFTKLPPVLTFELSRFEFNQSLGQPEKIHNKLEFPEIIYMDRFMYK 377

  Fly   628 ------------------------------------NR--------------------------- 629
                                                ||
 Frog   378 NKELMRRKHSETRRLKGCIDHLNQKLESYLKYGSGPNRCPLPDMLQYVLEFANTKSAEWCPPTEV 442

  Fly   630 -------SGNSGEQNSQ--LNGTV---------DDCSTADSGSAM---------------EDDNL 661
                   :|::|..::|  .||.|         ||....:|.|::               ||...
 Frog   443 VTTSQSATGSTGSLDAQPLQNGFVGNNDTETSNDDSPKCESTSSLPPFVGHTVPNDCIPAEDPTH 507

  Fly   662 SSGVVTTASS---------SQHENDLNDEDEGIDMSSSTSKSAK-----QGSGPYLYELFAIMIH 712
            .|..:....|         ::.|.|:.|..:.|   :|.:||.:     |......|.|.|:::|
 Frog   508 GSDTLEEIRSVAACLQRWRTEVEKDIQDLKDSI---ASCTKSIEEVFIDQDLSQVPYRLHAVLVH 569

  Fly   713 SGSASGGHYYAYIKDFDNNEWFCFNDQNVTSITQEDIQR-SFGGPNGSYYSSAYTSSTNAYMLMY 776
            .|.|:.|||:|||.......|..:||.:||....|::.| |:||          ..:.:||.|||
 Frog   570 EGQANAGHYWAYIYSHSRCCWLKYNDVSVTEANWEELVRDSYGG----------MRNASAYCLMY 624

  Fly   777 RQVDAKRNELVAKVADFPEHIKTLLPKLHSEEETRVSRLGRHITVTDLALPDLYKPRVYFYNPSL 841
                 ..|:|...:||....::..:..||                                 |:|
 Frog   625 -----INNKLPYLIADHEGELEDKINALH---------------------------------PAL 651

  Fly   842 KKMKITRVYV---SQSFNINLVLMSAYEMLNVEQFAPLSRCRLVAYNSSMDTIIQSLESCTDPAL 903
                  :.||   :|.|:..:..........:.|...:.....|.:.|..:..: ..|.|:....
 Frog   652 ------QCYVQEDNQRFDQEMTEWEEAHSCKIPQIESVGSSESVDHPSRNNASL-CCEECSRSLS 709

  Fly   904 TE--LRAAQNYSLDFLLEYRAEDQEFEVYPPNGITWYVFKVDLSTMAMDGPFLVYSAAREREASD 966
            :|  :.|.:..:|       |..:..|.|..||:          .:|:..|    :.....|||
 Frog   710 SEHAMIAKEQTAL-------AITKTAESYERNGV----------EVALKEP----TKPETGEAS- 752

  Fly   967 VLRRSIALRLHISEQQFLLATVRATVPKAFVSYDPHPTPEALQHLQNMANTQFKSITYFYLNVPN 1031
                              |:....|..:   ..:|.|:.:       ::..:..|:....:.. :
 Frog   753 ------------------LSDASLTAQE---ETEPQPSSQ-------LSEVEIPSVGKILVRT-D 788

  Fly  1032 TDAATLEMLGVPTVESVECA--SGGDVVDAAMMNGVAPGHMSSSNDYDWRRYKRDLVEPMSQPSP 1094
            ||....||:..|.::.|..|  ....|.|   .:|...|.:.:.::...|.|:....||.....|
 Frog   789 TDGYNEEMMLCPAMQGVIFAILKARQVFD---RDGPEAGLVKAFHEEYSRLYQLSKEEPSPSSDP 850

  Fly  1095 SHGH------ESNSEDSSLSDGDRTLVE---TDNMAHRGGGDSQVSSTSHSPQLSSPEDEAASHD 1150
            ...|      ::.:.|..:   :|||:|   ..|:::.....|.:.......:...|:|
 Frog   851 RLQHVLIYFFQNKAPDRVI---ERTLLEQFADKNLSYNERSISIMKVAQAKLREIGPDD------ 906

  Fly  1151 AMMRVHAYCNGNGSYAAADVVDPLLL-----------PTSTNHFFYATKVEC-VDVVGTGSSSGH 1203
              |.:..|...:..|:....|...||           ..:..:..||  .:| ..:|.:|.|.|.
 Frog   907 --MDMKEYQKWHEDYSLFRKVSVYLLTGLELYQNEKWQEALTYLVYA--YQCNRSLVSSGESLGV 967

  Fly  1204 Q---------------SDEEAQLRKPTRAYKLLVGTHMRMGAFKKHIEQLIQVPAAHFKLQRKHD 1253
            :               :|:.|.|.:.::..::..|..:        :..|| :|..|...
 Frog   968 EETLIQLYRRKCLLKLNDKAATLFESSQEEQVSEGISI--------MNDLI-IPCMHLIF----- 1018

  Fly  1254 NNLSNNQNNSLVHLIEGETLTVELGKTLEPDEFKAKI-HFL-RLADIDNE 1301
            ||..:.::.|.:..:.....:. ||:.:: |..:.|: .|| ||.|..::
 Frog  1019 NNKISEEDLSAIEEMRNRWCSY-LGQDID-DNLQMKLGQFLPRLLDCSSD 1066

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp47	NP_523937.2	TEBP_beta	<119..234	CDD:254188
		Rib_recp_KP_reg	122..265	CDD:282899
		peptidase_C19C	394..780	CDD:239124	117/522 (22%)
		UCH	395..776	CDD:278850	115/518 (22%)
usp28	XP_002937867.3	UBA_UBP28	1..42	CDD:270540
		UBP14	<138..611	CDD:227532	109/495 (22%)
		Peptidase_C19I	139..625	CDD:239130	116/523 (22%)
		USP28_C	825..1104	CDD:380452	48/271 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910