Protein Alignment DnaJ-1 and SIS1

DIOPT Version :9

• Sequence 1: NP_523936.2
• Gene: DnaJ-1 / 38643
• FlyBaseID: FBgn0263106
• Length: 334
• Species: Drosophila melanogaster
• Sequence 2: NP_014391.1
• Gene: SIS1 / 855725
• SGDID: S000004952
• Length: 352
• Species: Saccharomyces cerevisiae
• Alignment Length: 361
• Identity: 130/361 - (36%)
• Similarity: 192/361 - (53%)
• Gaps: 54/361 - (14%)

  Fly     6 YKILGLERKASDDEIKKAYRKLALKYHPDKNKSPQAE-ERFKEIAEAYEVLSDKKKRDIFDNYGE 69
            |.:||:...|::.|:||.|||.||||||||   |..: |:||||:||:|:|:|.:||:|:|.||.
Yeast     8 YDLLGVSPSANEQELKKGYRKAALKYHPDK---PTGDTEKFKEISEAFEILNDPQKREIYDQYGL 69

  Fly    70 DGLKGGQP-----GPDGGGQPGAY---TYQFHG-------DPRATFAQFFGSSDPFG-------- 111
            :..:.|.|     ||.|.|..|.:   ...|.|       |....|:||||.|.|||
Yeast    70 EAARSGGPSFGPGGPGGAGGAGGFPGGAGGFSGGHAFSNEDAFNIFSQFFGGSSPFGGADDSGFS 134

  Fly   112 -AFFTGGDNMFSGGQGGNTNEIFWNIGGDDMFAFNAQAPSRKRQQDPPIEHDLFVSLEEVDKGCI 175
             :.:..|.....||..|....:...:||.. ..|.:.:.|....::..::.:|.||||::..|..
Yeast   135 FSSYPSGGGAGMGGMPGGMGGMHGGMGGMP-GGFRSASSSPTYPEEETVQVNLPVSLEDLFVGKK 198

  Fly   176 KKMKISRMATGSNGPY--KEEKVLRITVKPGWKAGTKITFPQEGDSAP----NKTPADIVFIIRD 234
            |..||     |..||:  .|:..:.|.:|||||||||||:..:||..|    .||   :.|:|::
Yeast   199 KSFKI-----GRKGPHGASEKTQIDIQLKPGWKAGTKITYKNQGDYNPQTGRRKT---LQFVIQE 255

  Fly   235 KPHSLFKREGIDLKYTAQISLKQALCGALVSVPTLQG-----SRIQVNPNHEIIKPTTTRRINGL 294
            |.|..|||:|.||.||..:|.|::|.|...::.|:.|     ||:|.      ::|:.|....|.
Yeast   256 KSHPNFKRDGDDLIYTLPLSFKESLLGFSKTIQTIDGRTLPLSRVQP------VQPSQTSTYPGQ 314

  Fly   295 GLPVPKEPSRRGDLIVSFDIKFPDTLAPSLQNQLSE 330
            |:|.||.||:||:|||.:.:.:|.:|..:.:..:.|
Yeast   315 GMPTPKNPSQRGNLIVKYKVDYPISLNDAQKRAIDE 350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DnaJ-1	NP_523936.2	DnaJ	1..333	CDD:223560	130/361 (36%)
		DnaJ	4..65	CDD:278647	32/59 (54%)
		DnaJ_C	157..320	CDD:199909	66/173 (38%)
SIS1	NP_014391.1	DnaJ	2..350	CDD:223560	129/359 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344993
Domainoid	1	1.000	107	1.000	Domainoid score	I1436
eggNOG	1	0.900	-	-		E2759_KOG0714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	201	1.000	Inparanoid score	I853
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000274
OrthoInspector	1	1.000	-	-		otm46486
orthoMCL	1	0.900	-	-		OOG6_100302
Panther	1	1.100	-	-	O	PTHR24078
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1020
SonicParanoid	1	1.000	-	-		X227
TreeFam	0	0.000	Not matched by this tool.
	11	10.820