DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DnaJ-1 and Dnaja2

DIOPT Version :9

Sequence 1:	NP_523936.2	Gene:	DnaJ-1 / 38643	FlyBaseID:	FBgn0263106	Length:	334	Species:	Drosophila melanogaster
Sequence 2:	NP_114468.2	Gene:	Dnaja2 / 84026	RGDID:	71001	Length:	412	Species:	Rattus norvegicus

Alignment Length:	395	Identity:	127/395 - (32%)
Similarity:	182/395 - (46%)	Gaps:	113/395 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 YKILGLERKASDDEIKKAYRKLALKYHPDKNKSPQAEERFKEIAEAYEVLSDKKKRDIFDNYGED 70
            |.|||:...||::|:||||||||.:||||||  |.|.::||||:.||||||:.:||:::|.|||.
  Rat    10 YDILGVPPGASENELKKAYRKLAKEYHPDKN--PNAGDKFKEISFAYEVLSNPEKRELYDRYGEQ 72

  Fly    71 GLKGGQPGPDGGGQPGAYTYQFHGDPRATFAQFFGSSDPFGAFFTGGDNMFSGGQGGNTNEIFWN 135
            ||:   .|..|||                     |..|.|...|.||...|.|.|..:.|
  Rat    73 GLR---EGSGGGG---------------------GMDDIFSHIFGGGLFGFMGNQSRSRN----- 108

  Fly   136 IGGDDMFAFNAQAPSRKRQQDPPIEHDLFVSLEEVDKGCIKKMKISR------------------ 182
                          .|:|.:|  :.|.|.||||::..|...|:::|:
  Rat   109 --------------GRRRGED--MMHPLKVSLEDLYNGKTTKLQLSKNVLCSACSGQGGKSGAVQ 157

  Fly   183 ----------------MATG-----------SNGP------------------YKEEKVLRITVK 202
                            :|.|           .||.                  .||.|:|.:.|.
  Rat   158 KCSACRGRGVRIMIRQLAPGMVQQMQSVCSDCNGEGEVINEKDRCKKCEGKKVIKEVKILEVHVD 222

  Fly   203 PGWKAGTKITFPQEGDSAPNKTPADIVFIIRDKPHSLFKREGIDLKYTAQISLKQALCGALVSVP 267
            .|.|.|.:|||..|.|.||...|.|||.::::|.|.:|:|:|.||..|.:|.|.:||||...:..
  Rat   223 KGMKHGQRITFTGEADQAPGVEPGDIVLLLQEKEHEVFQRDGNDLHMTYKIGLVEALCGFQFTFK 287

  Fly   268 TLQGSRIQVN-PNHEIIKPTTTRRINGLGLPVPKEPSRRGDLIVSFDIKFPDT--LAPSLQNQLS 329
            .|...:|.|. |..::|:|...|.:.|.|:|..:.|..:|||.:.||::||:.  :.|...::|.
  Rat   288 HLDARQIVVKYPPGKVIEPGCVRVVRGEGMPQYRNPFEKGDLYIKFDVQFPENNWINPDKLSELE 352

  Fly   330 ELLPN 334
            :|||:
  Rat   353 DLLPS 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DnaJ-1	NP_523936.2	DnaJ	1..333	CDD:223560	125/392 (32%)
		DnaJ	4..65	CDD:278647	35/58 (60%)
		DnaJ_C	157..320	CDD:199909	64/228 (28%)
Dnaja2	NP_114468.2	PTZ00037	4..412	CDD:240236	127/395 (32%)
		CXXCXGXG motif	143..150		0/6 (0%)
		CXXCXGXG motif	159..166		0/6 (0%)
		CXXCXGXG motif	186..193		2/6 (33%)
		CXXCXGXG motif	202..209		0/6 (0%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	365..412
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53515
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920