DRSC/TRiP Functional Genomics Resources

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Protein Alignment DnaJ-1 and Dnajb4

DIOPT Version :9

Sequence 1:NP_523936.2 Gene:DnaJ-1 / 38643 FlyBaseID:FBgn0263106 Length:334 Species:Drosophila melanogaster
Sequence 2:NP_001343292.1 Gene:Dnajb4 / 67035 MGIID:1914285 Length:337 Species:Mus musculus


Alignment Length:346 Identity:186/346 - (53%)
Similarity:243/346 - (70%) Gaps:24/346 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MGKDFYKILGLERKASDDEIKKAYRKLALKYHPDKNKSPQAEERFKEIAEAYEVLSDKKKRDIFD 65
            ||||:|.|||:::.|:|:::||||||.|||:||||||||||||:|||:|||||||||.|||:|:|
Mouse     1 MGKDYYHILGIDKGATDEDVKKAYRKQALKFHPDKNKSPQAEEKFKEVAEAYEVLSDPKKREIYD 65

  Fly    66 NYGEDGLKGGQPGPDGGGQPGAYTYQFHGDPRATFAQFFGSSDPFGAFFTGGDNMFSGGQGGNTN 130
            .:||:|||||..|.||.|  |.:.|.|||||.||||.|||.|:||..||  |..|   |.|.::.
Mouse    66 QFGEEGLKGGAGGTDGQG--GTFRYTFHGDPHATFAAFFGGSNPFEIFF--GRRM---GGGRDSE 123

  Fly   131 EIFWNIGGDDMFAF-----------NAQAPSRKRQQDPPIEHDLFVSLEEVDKGCIKKMKISRMA 184
            |:  .|.||...||           |:..|||.: |||||.|:|.|||||:..||.|:|||||..
Mouse   124 EM--EIDGDPFSAFGFSMNGYPRDRNSVGPSRLK-QDPPIIHELKVSLEEIYSGCTKRMKISRKR 185

  Fly   185 TGSNG-PYK-EEKVLRITVKPGWKAGTKITFPQEGDSAPNKTPADIVFIIRDKPHSLFKREGIDL 247
            ...:| .|: |:|:|.|.:|.|||.|||||||:|||..||..||||||:|:||.|..|||:|.::
Mouse   186 LNPDGRSYRSEDKILTIEIKKGWKEGTKITFPREGDETPNSIPADIVFVIKDKEHPKFKRDGSNI 250

  Fly   248 KYTAQISLKQALCGALVSVPTLQGSRIQVNPNHEIIKPTTTRRINGLGLPVPKEPSRRGDLIVSF 312
            .|||:|||::||||..::|||:.|..:.::.. :|:||...||:.|.|||.||.|.:||||::.|
Mouse   251 VYTAKISLREALCGCSLNVPTMDGRNLPMSVT-DIVKPGMRRRVIGYGLPFPKNPDQRGDLLIEF 314

  Fly   313 DIKFPDTLAPSLQNQLSELLP 333
            |:.|||.::.:.:..|.:.||
Mouse   315 DVSFPDVISAASKEILRKHLP 335

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DnaJ-1NP_523936.2 DnaJ 1..333 CDD:223560 184/344 (53%)
DnaJ 4..65 CDD:278647 44/60 (73%)
DnaJ_C 157..320 CDD:199909 89/164 (54%)
Dnajb4NP_001343292.1 DnaJ 1..332 CDD:223560 184/341 (54%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 190 1.000 Domainoid score I3258
eggNOG 1 0.900 - - E2759_KOG0714
Hieranoid 1 1.000 - -
Homologene 1 1.000 - - H100610
Inparanoid 1 1.050 371 1.000 Inparanoid score I2098
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG53515
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000274
OrthoInspector 1 1.000 - - mtm8681
orthoMCL 1 0.900 - - OOG6_100302
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R1020
SonicParanoid 1 1.000 - - X227
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
1312.760

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