DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DnaJ-1 and Dnajb7

DIOPT Version :9

Sequence 1:	NP_523936.2	Gene:	DnaJ-1 / 38643	FlyBaseID:	FBgn0263106	Length:	334	Species:	Drosophila melanogaster
Sequence 2:	NP_067292.2	Gene:	Dnajb7 / 57755	MGIID:	1914012	Length:	312	Species:	Mus musculus

Alignment Length:	178	Identity:	62/178 - (34%)
Similarity:	93/178 - (52%)	Gaps:	31/178 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 DFYKILGLERKASDDEIKKAYRKLALKYHPDKN--KSPQAEERFKEIAEAYEVLSDKKKRDIFDN 66
            |:|::||::|.||.::||:||||:|||:|||||  ...:||.:|||:||||||||:.:||||:|.
Mouse     3 DYYEVLGVQRYASPEDIKRAYRKVALKWHPDKNPENKEEAERKFKEVAEAYEVLSNVEKRDIYDK 67

  Fly    67 YGEDGLKGGQPGPDGGGQPGAYTYQFHGDPRATFAQFFGSSDPFGAFFTGGDNMFSGGQGGNTNE 131
            ||::||.|.........:...:|::...|   .|.:.||..|||..      ::|.....|..|
Mouse    68 YGKEGLDGRGASHLDDEREYRFTFRKADD---VFKEIFGERDPFSF------HLFEDSLEGLLN- 122

  Fly   132 IFWNIGGDDMFAFNAQAPSRKRQQ------DPPIEHDLFVSLEEVDKG 173
                         ::::||..|.:      ....:|.....|...|.|
Mouse   123 -------------SSRSPSGSRGRGAGSHVSRAYDHPALSGLSSYDTG 157

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DnaJ-1	NP_523936.2	DnaJ	1..333	CDD:223560	62/178 (35%)
		DnaJ	4..65	CDD:278647	38/62 (61%)
		DnaJ_C	157..320	CDD:199909	4/17 (24%)
Dnajb7	NP_067292.2	DnaJ	3..66	CDD:278647	38/62 (61%)
Dnajb7	NP_067292.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	272..312
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167844322
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740