DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DnaJ-1 and Dnajb12

DIOPT Version :9

Sequence 1:	NP_523936.2	Gene:	DnaJ-1 / 38643	FlyBaseID:	FBgn0263106	Length:	334	Species:	Drosophila melanogaster
Sequence 2:	NP_001361685.1	Gene:	Dnajb12 / 56709	MGIID:	1931881	Length:	378	Species:	Mus musculus

Alignment Length:	149	Identity:	57/149 - (38%)
Similarity:	72/149 - (48%)	Gaps:	37/149 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 KDFYKILGLERKASDDEIKKAYRKLALKYHPDKNKSPQAEERFKEIAEAYEVLSDKKKRDIFDNY 67
            ||:|:|||:.|.|||:::||||||||||:|||||.:|.|.|.||.|..||.|||:.:||..:|.:
Mouse   110 KDYYEILGVSRSASDEDLKKAYRKLALKFHPDKNHAPGATEAFKAIGTAYAVLSNPEKRKQYDQF 174

  Fly    68 GEDGLKGGQPGPDGGGQPGAYTYQFHGDPRATFAQFFGSSDPFGAFFTGG--------------- 117
            |:|..:..:.|            ..|||....|.......|.|..||.||
Mouse   175 GDDKSQAARHG------------HSHGDFHRGFEADISPEDLFNMFFGGGFPSSNVHVYSNGRMR 227

  Fly   118 ----------DNMFSGGQG 126
                      ||...||.|
Mouse   228 YTYQQRQDRRDNQGDGGLG 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DnaJ-1	NP_523936.2	DnaJ	1..333	CDD:223560	57/149 (38%)
		DnaJ	4..65	CDD:278647	37/60 (62%)
		DnaJ_C	157..320	CDD:199909
Dnajb12	NP_001361685.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	45..97
		DnaJ_bact	111..>237	CDD:274090	51/137 (37%)
		DUF1977	269..369	CDD:370429
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167844338
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740