DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DnaJ-1 and dnajb14

DIOPT Version :9

Sequence 1:	NP_523936.2	Gene:	DnaJ-1 / 38643	FlyBaseID:	FBgn0263106	Length:	334	Species:	Drosophila melanogaster
Sequence 2:	NP_001016588.1	Gene:	dnajb14 / 549342	XenbaseID:	XB-GENE-952313	Length:	375	Species:	Xenopus tropicalis

Alignment Length:	199	Identity:	68/199 - (34%)
Similarity:	92/199 - (46%)	Gaps:	40/199 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 KDFYKILGLERKASDDEIKKAYRKLALKYHPDKNKSPQAEERFKEIAEAYEVLSDKKKRDIFDNY 67
            |.:|::||:...|.::::||||||||||:|||||.:|.|.|.||:|..||.|||:.:||..:|
Frog   105 KTYYEVLGVSTDAGEEDLKKAYRKLALKFHPDKNHAPGATEAFKKIGNAYAVLSNPEKRKQYD-- 167

  Fly    68 GEDGLKGGQPGPDGGGQPGAYTYQ--FHGD--PRATFAQFFGSSDPFGAF--FTGGDNMFSGGQ- 125
                |.|.:.......:.|.:.|.  |..|  |...|..|||...|.|:.  |:.|...:|..|
Frog   168 ----LTGSEDQMQNNHRNGGFDYHRGFEADITPEDLFNMFFGGGFPSGSVHTFSNGRARYSHHQH 228

  Fly   126 ---GGNTNEIFWNIGGDDMFAFNAQAPSRKRQQDPPIEHDLFVSLEEVDKGCIKKMKISRMATGS 187
               .|:..|.....||..||.           |..||...:.|||            :|:... |
Frog   229 HHHSGHDREDERADGGFSMFI-----------QLMPIIVLILVSL------------LSQFMV-S 269

  Fly   188 NGPY 191
            |.||
Frog   270 NPPY 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DnaJ-1	NP_523936.2	DnaJ	1..333	CDD:223560	68/199 (34%)
		DnaJ	4..65	CDD:278647	32/60 (53%)
		DnaJ_C	157..320	CDD:199909	10/35 (29%)
dnajb14	NP_001016588.1	FliS	6..>34	CDD:382133
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	48..95
		DnaJ_bact	107..>212	CDD:274090	45/110 (41%)
		DUF1977	269..367	CDD:370429	4/5 (80%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910