DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DnaJ-1 and dnajc3

DIOPT Version :9

Sequence 1:	NP_523936.2	Gene:	DnaJ-1 / 38643	FlyBaseID:	FBgn0263106	Length:	334	Species:	Drosophila melanogaster
Sequence 2:	XP_012812335.1	Gene:	dnajc3 / 496977	XenbaseID:	XB-GENE-997043	Length:	504	Species:	Xenopus tropicalis

Alignment Length:	124	Identity:	51/124 - (41%)
Similarity:	66/124 - (53%)	Gaps:	27/124 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 KDFYKILGLERKASDDEIKKAYRKLALKYHP----DKNKSPQAEERFKEIAEAYEVLSDKKKRDI 63
            :|:|||||::|.|...||.|||||||.::||    |:.:..:||::|.:||.|.|||:|.:||..
Frog   393 RDYYKILGVKRNAKKQEIIKAYRKLAQQWHPDNFQDEEEKKKAEKKFIDIASAKEVLTDPEKRSR 457

  Fly    64 FDNYGEDGLKGGQPGPDGGGQPGAYTYQFHG--------DPRATFAQFFGSSDPFGAFF 114
            || .|||.|       |...|.||....||.        :|       |||..||...|
Frog   458 FD-AGEDPL-------DPESQQGAGGPHFHRGWNQWQGFNP-------FGSGGPFSFKF 501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DnaJ-1	NP_523936.2	DnaJ	1..333	CDD:223560	51/124 (41%)
		DnaJ	4..65	CDD:278647	32/64 (50%)
		DnaJ_C	157..320	CDD:199909
dnajc3	XP_012812335.1	TPR repeat	37..65	CDD:276809
		PEP_TPR_lipo	47..>366	CDD:274350
		TPR repeat	70..100	CDD:276809
		TPR repeat	105..133	CDD:276809
		TPR repeat	154..182	CDD:276809
		TPR repeat	187..217	CDD:276809
		TPR repeat	222..250	CDD:276809
		TPR repeat	256..281	CDD:276809
		TPR repeat	300..335	CDD:276809
		TPR repeat	340..368	CDD:276809
		TPR repeat	374..397	CDD:276809	1/3 (33%)
		DnaJ	392..>494	CDD:223560	47/115 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910