Protein Alignment DnaJ-1 and DNAJB2

DIOPT Version :9

• Sequence 1: NP_523936.2
• Gene: DnaJ-1 / 38643
• FlyBaseID: FBgn0263106
• Length: 334
• Species: Drosophila melanogaster
• Sequence 2: NP_006727.2
• Gene: DNAJB2 / 3300
• HGNCID: 5228
• Length: 324
• Species: Homo sapiens
• Alignment Length: 365
• Identity: 104/365 - (28%)
• Similarity: 149/365 - (40%)
• Gaps: 112/365 - (30%)

  Fly     5 FYKILGLERKASDDEIKKAYRKLALKYHPDKNKSPQ--AEERFKEIAEAYEVLSDKKKRDIFDNY 67
            :|:||.:.|.||.|:||||||:.||::|||||...:  ||::|||:||||||||||.||:|:|.|
Human     4 YYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDRY 68

  Fly    68 GEDGLKGGQPGPD----GGGQPGAYTYQFHGDPRATFAQFFGSSDPF------------------ 110
            |.:||.|...||.    |.|.|| :|:.|. .|...|.:||||.|||
Human    69 GREGLTGTGTGPSRAEAGSGGPG-FTFTFR-SPEEVFREFFGSGDPFAELFDDLGPFSELQNRGS 131

  Fly   111 ---GAFFTGGDNM------------FSGGQGGNTNEIFWNIGGDDMFAFNAQAPSRK----RQQD 156
               |.|||...:.            ||.|.|.     |.::.....|....:..:|:    .|:.
Human   132 RHSGPFFTFSSSFPGHSDFSSSSFSFSPGAGA-----FRSVSTSTTFVQGRRITTRRIMENGQER 191

  Fly   157 PPIEHDLFVSLEEVDKGCIKKMKIS----RMATGSNGPYKEEKVLRITVKPGWKAGTKITFPQEG 217
            ..:|.|          |.:|.:.|:    .:|.|.....:|::. .:|.:.|   ||::
Human   192 VEVEED----------GQLKSVTINGVPDDLALGLELSRREQQP-SVTSRSG---GTQV------ 236

  Fly   218 DSAPNKTPADIVFIIRDKPHSLFKREGIDLKYTAQISLKQAL----CGALVSVPTLQGSRIQVNP 278
            ...|...|.|         ..|.:.|.:.|.....:|..:|.    .|...:....||
Human   237 QQTPASCPLD---------SDLSEDEDLQLAMAYSLSEMEAAGKKPAGGREAQHRRQG------- 285

  Fly   279 NHEIIKPTTTRRINGLG-------------LPVPKEPSRR 305
                 :|....:..|||             .|.|:|.:.|
Human   286 -----RPKAQHQDPGLGGTQEGARGEATKRSPSPEEKASR 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DnaJ-1	NP_523936.2	DnaJ	1..333	CDD:223560	104/365 (28%)
		DnaJ	4..65	CDD:278647	38/61 (62%)
		DnaJ_C	157..320	CDD:199909	31/170 (18%)
DNAJB2	NP_006727.2	DnaJ	3..>110	CDD:223560	57/107 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	70..90		7/19 (37%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	218..324		24/134 (18%)
		CAAX motif. /evidence=ECO:0000269|PubMed:12754272	321..324		104/365 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154087
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740