DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DnaJ-1 and Dnajb5

DIOPT Version :9

Sequence 1:	NP_523936.2	Gene:	DnaJ-1 / 38643	FlyBaseID:	FBgn0263106	Length:	334	Species:	Drosophila melanogaster
Sequence 2:	XP_038966057.1	Gene:	Dnajb5 / 313811	RGDID:	1307453	Length:	420	Species:	Rattus norvegicus

Alignment Length:	361	Identity:	183/361 - (50%)
Similarity:	237/361 - (65%)	Gaps:	43/361 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGKDFYKILGLERKASDDEIKKAYRKLALKYHPDKNKSPQAEERFKEIAEAYEVLSDKKKRDIFD 65
            ||||:|||||:...|::|||||||||:||||||||||.|.|||:||||||||:||||.|||.::|
  Rat    73 MGKDYYKILGIPSGANEDEIKKAYRKMALKYHPDKNKEPNAEEKFKEIAEAYDVLSDPKKRSLYD 137

  Fly    66 NYGEDGLKGGQPGPDGGGQPGAYTYQFHGDPRATFAQFFGSSDPFGAFFTGGDNM--FSGGQGGN 128
            .|||:|||.|  |...||..|::.|.|||||.||||.|||.|:||..||....:.  |||
  Rat   138 QYGEEGLKTG--GGTSGGSGGSFHYTFHGDPHATFASFFGGSNPFDIFFASSRSTRPFSG----- 195

  Fly   129 TNEIFWNIGGDDM--------------FAFNA------QAPS----RKRQQDPPIEHDLFVSLEE 169
                   ...|||              |.||.      :||.    |::.||||:.|:|.|||||
  Rat   196 -------FDPDDMDVDEDEDPFGAFGRFGFNGLSRGPRRAPEPLYPRRKVQDPPVVHELRVSLEE 253

  Fly   170 VDKGCIKKMKISRMATGSNG--PYKEEKVLRITVKPGWKAGTKITFPQEGDSAPNKTPADIVFII 232
            :..|..|:|||:|.....:|  ...|:|:|.|.:|.|||.|||||||:|||:.|:..||||||::
  Rat   254 IYHGSTKRMKITRRRLNPDGRTVRTEDKILHIVIKRGWKEGTKITFPKEGDATPDNIPADIVFVL 318

  Fly   233 RDKPHSLFKREGIDLKYTAQISLKQALCGALVSVPTLQGSRIQVNPNHEIIKPTTTRRINGLGLP 297
            :||||:.|:|:|.::.|:|.||||:||||..|::||:.| |:...|.:::|||.|.:|:.|.|||
  Rat   319 KDKPHAHFRRDGTNVLYSALISLKEALCGCTVNIPTIDG-RVIPLPCNDVIKPGTVKRLRGEGLP 382

  Fly   298 VPKEPSRRGDLIVSFDIKFPDTLAPSLQNQLSELLP 333
            .||.|::||||||.|.::|||.|.|..:..|.:.||
  Rat   383 FPKVPTQRGDLIVEFKVRFPDRLTPQTRQILKQHLP 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DnaJ-1	NP_523936.2	DnaJ	1..333	CDD:223560	181/359 (50%)
		DnaJ	4..65	CDD:278647	45/60 (75%)
		DnaJ_C	157..320	CDD:199909	86/164 (52%)
Dnajb5	XP_038966057.1	DnaJ	72..415	CDD:223560	181/356 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347706
Domainoid	1	1.000	190	1.000	Domainoid score	I3167
eggNOG	1	0.900	-	-		E2759_KOG0714
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	371	1.000	Inparanoid score	I2057
OMA	1	1.010	-	-		QHG53515
OrthoDB	1	1.010	-	-		D1393097at2759
OrthoFinder	1	1.000	-	-		FOG0000274
OrthoInspector	1	1.000	-	-		mtm8916
orthoMCL	1	0.900	-	-		OOG6_100302
Panther	1	1.100	-	-	O	PTHR24078
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X227
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.810