Protein Alignment DnaJ-1 and DNAJB5

DIOPT Version :10

• Sequence 1: NP_523936.2
• Gene: DnaJ-1 / 38643
• FlyBaseID: FBgn0263106
• Length: 334
• Species: Drosophila melanogaster
• Sequence 2: NP_001128477.1
• Gene: DNAJB5 / 25822
• HGNCID: 14887
• Length: 420
• Species: Homo sapiens
• Alignment Length: 361
• Identity: 183/361 - (50%)
• Similarity: 237/361 - (65%)
• Gaps: 43/361 - (11%)

  Fly     1 MGKDFYKILGLERKASDDEIKKAYRKLALKYHPDKNKSPQAEERFKEIAEAYEVLSDKKKRDIFD 65
            ||||:|||||:...|::|||||||||:||||||||||.|.|||:||||||||:||||.|||.::|
Human    73 MGKDYYKILGIPSGANEDEIKKAYRKMALKYHPDKNKEPNAEEKFKEIAEAYDVLSDPKKRGLYD 137

  Fly    66 NYGEDGLKGGQPGPDGGGQPGAYTYQFHGDPRATFAQFFGSSDPFGAFFTGGDNM--FSGGQGGN 128
            .|||:|||.|  |...||..|::.|.|||||.||||.|||.|:||..||....:.  |||
Human   138 QYGEEGLKTG--GGTSGGSSGSFHYTFHGDPHATFASFFGGSNPFDIFFASSRSTRPFSG----- 195

  Fly   129 TNEIFWNIGGDDM--------------FAFNA------QAPS----RKRQQDPPIEHDLFVSLEE 169
                   ...|||              |.||.      :||.    |::.||||:.|:|.|||||
Human   196 -------FDPDDMDVDEDEDPFGAFGRFGFNGLSRGPRRAPEPLYPRRKVQDPPVVHELRVSLEE 253

  Fly   170 VDKGCIKKMKISRMATGSNG--PYKEEKVLRITVKPGWKAGTKITFPQEGDSAPNKTPADIVFII 232
            :..|..|:|||:|.....:|  ...|:|:|.|.:|.|||.|||||||:|||:.|:..||||||::
Human   254 IYHGSTKRMKITRRRLNPDGRTVRTEDKILHIVIKRGWKEGTKITFPKEGDATPDNIPADIVFVL 318

  Fly   233 RDKPHSLFKREGIDLKYTAQISLKQALCGALVSVPTLQGSRIQVNPNHEIIKPTTTRRINGLGLP 297
            :||||:.|:|:|.::.|:|.||||:||||..|::||:.| |:...|.:::|||.|.:|:.|.|||
Human   319 KDKPHAHFRRDGTNVLYSALISLKEALCGCTVNIPTIDG-RVIPLPCNDVIKPGTVKRLRGEGLP 382

  Fly   298 VPKEPSRRGDLIVSFDIKFPDTLAPSLQNQLSELLP 333
            .||.|::||||||.|.::|||.|.|..:..|.:.||
Human   383 FPKVPTQRGDLIVEFKVRFPDRLTPQTRQILKQHLP 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DnaJ-1	NP_523936.2	DnaJ_bact	4..332	CDD:274090	178/355 (50%)
DNAJB5	NP_001128477.1	DnaJ_bact	76..415	CDD:274090	178/353 (50%)