Protein Alignment DnaJ-1 and DNAJB4

DIOPT Version :9

• Sequence 1: NP_523936.2
• Gene: DnaJ-1 / 38643
• FlyBaseID: FBgn0263106
• Length: 334
• Species: Drosophila melanogaster
• Sequence 2: NP_001304028.1
• Gene: DNAJB4 / 11080
• HGNCID: 14886
• Length: 337
• Species: Homo sapiens
• Alignment Length: 346
• Identity: 194/346 - (56%)
• Similarity: 246/346 - (71%)
• Gaps: 24/346 - (6%)

  Fly     1 MGKDFYKILGLERKASDDEIKKAYRKLALKYHPDKNKSPQAEERFKEIAEAYEVLSDKKKRDIFD 65
            ||||:|.|||:|:.|||::|||||||.|||:||||||||||||:|||:|||||||||.|||:|:|
Human     1 MGKDYYCILGIEKGASDEDIKKAYRKQALKFHPDKNKSPQAEEKFKEVAEAYEVLSDPKKREIYD 65

  Fly    66 NYGEDGLKGGQPGPDGGGQPGAYTYQFHGDPRATFAQFFGSSDPFGAFFTGGDNMFSGGQGGNTN 130
            .:||:|||||..|.||.|  |.:.|.|||||.||||.|||.|:||..||  |..|   |.|.::.
Human    66 QFGEEGLKGGAGGTDGQG--GTFRYTFHGDPHATFAAFFGGSNPFEIFF--GRRM---GGGRDSE 123

  Fly   131 EIFWNIGGDDMFAF-----------NAQAPSRKRQQDPPIEHDLFVSLEEVDKGCIKKMKISRMA 184
            |:  .|.||...||           |:..|||.: ||||:.|:|.|||||:..||.|:|||||..
Human   124 EM--EIDGDPFSAFGFSMNGYPRDRNSVGPSRLK-QDPPVIHELRVSLEEIYSGCTKRMKISRKR 185

  Fly   185 TGSNG-PYK-EEKVLRITVKPGWKAGTKITFPQEGDSAPNKTPADIVFIIRDKPHSLFKREGIDL 247
            ..::| .|: |:|:|.|.:|.|||.|||||||:|||..||..||||||||:||.|..|||:|.::
Human   186 LNADGRSYRSEDKILTIEIKKGWKEGTKITFPREGDETPNSIPADIVFIIKDKDHPKFKRDGSNI 250

  Fly   248 KYTAQISLKQALCGALVSVPTLQGSRIQVNPNHEIIKPTTTRRINGLGLPVPKEPSRRGDLIVSF 312
            .|||:|||::||||..::||||.|..|.::.| :|:||...|||.|.|||.||.|.:||||::.|
Human   251 IYTAKISLREALCGCSINVPTLDGRNIPMSVN-DIVKPGMRRRIIGYGLPFPKNPDQRGDLLIEF 314

  Fly   313 DIKFPDTLAPSLQNQLSELLP 333
            ::.||||::.|.:..|.:.||
Human   315 EVSFPDTISSSSKEVLRKHLP 335

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DnaJ-1	NP_523936.2	DnaJ	1..333	CDD:223560	192/344 (56%)
		DnaJ	4..65	CDD:278647	47/60 (78%)
		DnaJ_C	157..320	CDD:199909	92/164 (56%)
DNAJB4	NP_001304028.1	DnaJ	1..332	CDD:223560	192/341 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	190	1.000	Domainoid score	I3265
eggNOG	1	0.900	-	-		E2759_KOG0714
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H100610
Inparanoid	1	1.050	371	1.000	Inparanoid score	I2129
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53515
OrthoDB	1	1.010	-	-		D1393097at2759
OrthoFinder	1	1.000	-	-		FOG0000274
OrthoInspector	1	1.000	-	-		mtm8440
orthoMCL	1	0.900	-	-		OOG6_100302
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1020
SonicParanoid	1	1.000	-	-		X227
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.770