Protein Alignment DnaJ-1 and DNAJB6

DIOPT Version :10

• Sequence 1: NP_523936.2
• Gene: DnaJ-1 / 38643
• FlyBaseID: FBgn0263106
• Length: 334
• Species: Drosophila melanogaster
• Sequence 2: XP_005249572.1
• Gene: DNAJB6 / 10049
• HGNCID: 14888
• Length: 334
• Species: Homo sapiens
• Alignment Length: 293
• Identity: 97/293 - (33%)
• Similarity: 135/293 - (46%)
• Gaps: 66/293 - (22%)

  Fly     4 DFYKILGLERKASDDEIKKAYRKLALKYHPDKN--KSPQAEERFKEIAEAYEVLSDKKKRDIFDN 66
            |:|::||::|.||.::|||||||||||:|||||  ...:||.:||::|||||||||.|||||:|.
Human     3 DYYEVLGVQRHASPEDIKKAYRKLALKWHPDKNPENKEEAERKFKQVAEAYEVLSDAKKRDIYDK 67

  Fly    67 YGEDGLKGGQPGPDGGGQPGAYTYQFHGDPRATFAQFFGSSDPF--------------------- 110
            ||::||.||..|......|..:.:.|. :|...|.:|||..|||
Human    68 YGKEGLNGGGGGGSHFDSPFEFGFTFR-NPDDVFREFFGGRDPFSFDFFEDPFEDFFGNRRGPRG 131

  Fly   111 ------GAFF-----------------TGGDNMFSGGQGGNTNEIFWNIGGDDMFAFNAQAPSRK 152
                  |:||                 ||..:..|.|.||.|:....:.||..|..|.:.:.|.|
Human   132 SRSRGTGSFFSAFSGFPSFGSGFSSFDTGFTSFGSLGHGGLTSFSSTSFGGSGMGNFKSISTSTK 196

  Fly   153 RQQDPPIEHDLFVS-----LEEVDKGCIKKMKISRMATGSNGPYKEEKVLR-ITVKPGWKAGTKI 211
            ......|.....|.     :|..:.|.:|.:.|:.:|  .:....||::.| ....|...||.:
Human   197 MVNGRKITTKRIVENGQERVEVEEDGQLKSLTINGVA--DDDALAEERMRRGQNALPAQPAGLR- 258

  Fly   212 TFPQEGDSAPNKTPADIVFIIRDKPHSLFKREG 244
                     |.|.|.. ..::|..||.|.:.||
Human   259 ---------PPKPPRP-ASLLRHAPHCLSEEEG 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DnaJ-1	NP_523936.2	DnaJ_bact	4..332	CDD:274090	97/293 (33%)
DNAJB6	XP_005249572.1	terminal_TopJ	3..>151	CDD:468284	62/148 (42%)
		DnaJ	3..66	CDD:395170	41/62 (66%)